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A randomized, double-blind, double-dummy multicenter trial compared cefpodoxime and cefaclor for the outpatient treatment of culture-proven acute CAP. Begin Test. Previous NCI Directors. Password Forgot password? Cefpodoxime binds penicillin-binding protein, disrupting cell wall synthesis. Podoxi Ciplox Belpro Trimox Pedicef. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. To select a suggestion, hit the enter key. Zoetis markets cefpodoxime proxetil under the trade name Simplicef for veterinary use. Keywords Vantim. Best Buy for Vantin support this Vantin, since with the careful surgical treatment of the wound, the correct choice of the method of plastic and Vantib proper surgical technique, the risk of infectious complications is negligible. Available for Android and iOS devices. Multicultural Media Outreach Program. Back Next. Cefpodoxime Film-coated Tablets Tablets should be Vanton orally with food to Vzntin absorption. Store the liquid medicine in a tightly-closed bottle in the refrigerator. Vantkn Treatment Editorial Board. Vantin is part of the drug class: Third generation cephalosporins. Try to eat as slowly as possible and enjoy your food. Cefpodoxime proxetil is a prodrug that is converted to cefpodoxime. It is also used to treat gonorrhea. It has activity against certain Gram-positive pathogens, including S. Cefpodoxime For more information on this medication choose from the list of selections below. Cefpodoxime is an oral third-generation cephalosporin antibiotic that received FDA approval many years ago. Advertising Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Cancer Health Disparities. This review focuses specifically on the use of cefpodoxime for community-acquired pneumonia caused by Streptococcus pneumoniae and Haemophilus influenzae including beta-lactamase-producing strains and uncomplicated urinary tract infections caused by Escherichia coliKlebsiella pneumoniaeProteus mirabilisor Staphylococcus saprophyticus. Cefpodoxime has been used to fight pathogenic bacteria responsible for causing gonorrhoea, tonsillitis, pneumonia, and bronchitis. DOI:

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Common use

Vantin is a semi-synthetic broad-spectrum antibiotic of cephalosporin group with bactericidal effect. It is active against many gram positive, aerobic and anaerobic microorganisms. Vantin is resistant to to beta-lactamase. Insusceptible to the medication are Streptococcus of D group; Staphylococcus resistant to meticyllin; Corynebacterium of J and K group; Pseudomonas (Pseudomonas aeruginosa); Listeria monocytogenes, Acinetobacter baumanii, Clostridium difficile and Bacteroides. Vantin is used to treat illnesses of upper respiratory system caused by the susceptible bacteria including tonsillitis, pharyngitis, acute sinusitis, acute bronchitis, pneumonia, exacerbation of chronic pneumonia especially in alcohol abusers, smokers and adults older than 65 y.o. Vantin is sometimes given with other antibiotics and as injections to prevent infections before, during, and after surgery.

Dosage and directions

This medication should be taken with food and big glass of water. Shake well the liquid suspension form of this medication before using and take it with or without food. Do not take Vantin in larger amounts or longer than it was recommended to you. Continue to take the drug even if you feel fine and your symptoms became better as the infection may not be completely treated.


Vantin is not expected to be harmful to an unborn baby though it is important to notify your doctor if you are pregnant or breastfeeding. Let your doctor know if you have kidney or colitis or other intestinal diseases in history. This medication may cause false positive result in urine glucose tests.


Hypersensitivity to cephalosporins. Vantin should be prescribed with cautiousness in patients how had allergy to penicillin antibiotics in history.

Possible side effect

Most common possible side effects besides allergy (hives, rash, swelling of face and tongue) are diarrhea, vomiting, abdominal pain, cough, wheezing, unusual bleeding or bruising, seizure, jaundice, confusion. In rare cases rash, itching, transient temporary moderate increase of liver transaminases and phosphotase activity.

Drug interaction

Medications blocking histamine H2-receptors (Ranitidine and others), antacids (aluminum hydroxide, sodium bicarbonate) diminish Vantin effect.

Missed dose

If you missed a dose of Vantin take it as soon as you remember in case it is almost time of your next dose. Skip the next dose and return to your regular schedule. Do not take up extra dose of the medication to compensate the missed dose.


Symptoms of overdose may be nausea, vomiting, stomach pain, and diarrhea. Seek for immediate medical help if you have serious signs listed above.


Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Keep the suspension liquid in a refrigerator not longer than 14 days but do not freeze it.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Lasix work and what pharmaceutical group does it belong to?

Lasix is a diuretic agent. Lasix causes a short term diuresis. Lasix action mechanism is associated with the reabsorbtion block of chloride and sodium ions in the Henle's loop.Lasix works by increasing excretion of K+, Ca2+, Mg2+ out of the organism. Hypotensive effect of the medication is associated with increased elimination of sodium and water.

Which conditions are treated with Lasix?

Lasix is used for the treatment of the following conditions:

  • Edema syndrome in chronic cardiac failure(II - III stage)
  • Cirrhosis
  • Kidney diseases
  • Cerebral edema
  • Hypertensive crisis
  • Hypertension
  • High calcium blood level

What should a patient know before using Lasix?

The Lasix should not be used in cases of:

  • Hypersensitivity
  • Severe renal failure
  • Acute liver failure
  • Ankylurethria
  • Acute glomerulonephritis
  • Hyperglycemic coma
  • Hyperuricemia
  • Arthragra
  • Decompensated mitral or aortal stenosis
  • Hypotension
  • Acute myocardial infarction
  • Pancreatitis
  • Digitalis intoxication

The drug should be used with caution in the following conditions:

  • Prostatic Hyperplasia
  • Systemic lupus erythematosus
  • Diabetes
  • Pregnancy
  • Breastfeeding

Which adverse effects may manifest when using the medication?

The side effects of Lasix include:

  • Cardiovascular system: hypotension, postural hypotension, collapse, tachycardia, arrhythmia, volume of blood circulation decrease.
  • Central nervous system: dizziness, headache, myasthenia, cramp in leg, paresthesia, apathy, adynamia, weakness, drowsiness,
  • Sense organs: vision and hearing disorders.
  • Gastrointestinal tract: appetite reduce, xerostomia, nausea, vomiting, constipations and diarrhea, pancreatitis.
  • Urinary system: oliguria, acute retention of urine, interstitial nephritis, erythrocyturia, decrease of sexual potency.
  • Allergic reactions: purpura, urticaria fever, exfoliative dermatitis, vasculitis, skin rash, shakes, fever.
  • Hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis, anemotrophy.
  • Water-electrolyte balance: hypovolemia, anhydration, hypokalemia, hyponatremia, hypomagnesemia, metabolic alkalosis.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Lasix?

The drug is affected by the following:

  • Immunodepresants
  • Aminoglycosides
  • Antimicrobial agents
  • Diuretics
  • Antineoplastics
  • Antimycotics
  • Antiulcer agents
  • Bronchodilating agents
  • Hypotensive preparations
  • Glucocorticosteroids
  • Cardiac glycosides

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Lasix is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.