Generic Sporanox (Itraconazole)
Sporanox
Sporanox is an azole antifungal medicine used used to treat blastomycosis, histoplasmosis and aspergillosis.
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Product Description

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Common use

Sporanox is an azole antifungal medicine which used used to treat three types of serious fungal infection: blastomycosis, histoplasmosis, and aspergillosis. Sporanox works by killing sensitive fungi by interfering with the formation of the fungal cell membrane. This medication is also prescribed for onychomycosis, which infects the toenails and fingernails.



Dosage and direction

Take it orally with or without food/milk. For the best result take it at the same time each day. Dosage of Sporanox is various from type of infection:

1. Treatment of Blastomycosis and Histoplasmosis:

The recommended dose for adults is 200 mg once daily. Do not use more than 400 mg daily.

For children - use it just after doctor's permission and dose has to be prescribed after consulting with your doctor.

2. Treatment of Aspergillosis:

The recommended dose for adults is of 200 to 400 mg.

For children - use it just after doctor's permission and dose has to be prescribed after consulting with your doctor.

3. Treatment in Life-Threatening Situations:

The recommended dose for adults is 200 mg three times daily (600 mg/day) be given for the first 3 days of treatment. Length of treatment should be more than three months and until clinical parameters and laboratory tests indicate that the active fungal infection has subsided.

For children - use it just after doctor's permission and dose has to be prescribed after consulting with your doctor.

4. Treatment of Onychomycosis (toenails with or without fingernail involvement):

The recommended dose fr adults is 200 mg once daily for 12 consecutive weeks.

For children - use it just after doctor's permission and dose has to be prescribed after consulting with your doctor.

5. Treatment of Onychomycosis (Ffngernails only) :

The recommended dose for adults is 2 treatment pulses, each consisting of 200 mg for 1 week.

For children - use it just after doctor's permission and dose has to be prescribed after consulting with your doctor.

Note: this instruction presented here just for review. It's very necessary to consult with your doctor before using. It help you to get best results.



Precautions

Sporanox can have a negative effect on the heart. It should not be used for fungal nail infections if your medical history include cardiac problems such as congestive heart failure. Before taking Sporanox, tell your doctor if your medical history include: a heart rhythm disorder, kidney or liver disease, a breathing disorder, cystic fibrosis, or a history of "Long QT syndrome." Do not take antacids within 1 hour before or 2 hours after taking Sporanox. Sporanox should not be used during pregnancy, becoming pregnant or lactating without doctor's advice. Do not use it before breast-feeding without doctor's permission.



Contraindications

Sporano is not allowed to people who are hypersensitive to itraconazole or similar medications such as fluconazole (Diflucan) or ketoconazole (Nizoral), if you have ever had congestive heart failure.

Possible side effect

They may include an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Also the most possible side effects include:

fever;

feeling short of breath, even with mild exertion;

swelling, rapid weight gain;

problems with hearing;

numbness or tingly feeling;

pain or burning when you urinate;

nausea, stomach pain, low fever, loss of appetite, weakness, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious include:

diarrhea, constipation, mild stomach pain;

mild itching or skin rash;

headache, dizziness;

runny nose or other cold symptoms.

If you experience one of them stop using Sporanox and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.



Drug interaction

Sporanox interact with follow list of drugs: cisapride, dihydroergotamine, dofetilide, ergonovine, ergotamine, lovastatin, methylergonovine, midazolam, nisoldipine, pimozide, quinidine, Quinidex, Quin-Release, simvastatin , or triazolam. Also note that interaction between two medications does not always mean that you must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.



Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not take double or extra doses. Take your usually dose next day in the same regularly time.



Overdose

Symptoms of Sporanox overdose are not known well, so if you experience any unusual symptom call your doctor immediately.

Storage

Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Lasix work and what pharmaceutical group does it belong to?

Lasix is a diuretic agent. Lasix causes a short term diuresis. Lasix action mechanism is associated with the reabsorbtion block of chloride and sodium ions in the Henle's loop.Lasix works by increasing excretion of K+, Ca2+, Mg2+ out of the organism. Hypotensive effect of the medication is associated with increased elimination of sodium and water.

Which conditions are treated with Lasix?

Lasix is used for the treatment of the following conditions:

  • Edema syndrome in chronic cardiac failure(II - III stage)
  • Cirrhosis
  • Kidney diseases
  • Cerebral edema
  • Hypertensive crisis
  • Hypertension
  • High calcium blood level

What should a patient know before using Lasix?

The Lasix should not be used in cases of:

  • Hypersensitivity
  • Severe renal failure
  • Acute liver failure
  • Ankylurethria
  • Acute glomerulonephritis
  • Hyperglycemic coma
  • Hyperuricemia
  • Arthragra
  • Decompensated mitral or aortal stenosis
  • Hypotension
  • Acute myocardial infarction
  • Pancreatitis
  • Digitalis intoxication

The drug should be used with caution in the following conditions:

  • Prostatic Hyperplasia
  • Systemic lupus erythematosus
  • Diabetes
  • Pregnancy
  • Breastfeeding

Which adverse effects may manifest when using the medication?

The side effects of Lasix include:

  • Cardiovascular system: hypotension, postural hypotension, collapse, tachycardia, arrhythmia, volume of blood circulation decrease.
  • Central nervous system: dizziness, headache, myasthenia, cramp in leg, paresthesia, apathy, adynamia, weakness, drowsiness,
  • Sense organs: vision and hearing disorders.
  • Gastrointestinal tract: appetite reduce, xerostomia, nausea, vomiting, constipations and diarrhea, pancreatitis.
  • Urinary system: oliguria, acute retention of urine, interstitial nephritis, erythrocyturia, decrease of sexual potency.
  • Allergic reactions: purpura, urticaria fever, exfoliative dermatitis, vasculitis, skin rash, shakes, fever.
  • Hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis, anemotrophy.
  • Water-electrolyte balance: hypovolemia, anhydration, hypokalemia, hyponatremia, hypomagnesemia, metabolic alkalosis.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Lasix?

The drug is affected by the following:

  • Immunodepresants
  • Aminoglycosides
  • Antimicrobial agents
  • Diuretics
  • Antineoplastics
  • Antimycotics
  • Antiulcer agents
  • Bronchodilating agents
  • Hypotensive preparations
  • Glucocorticosteroids
  • Cardiac glycosides
  • NSAID

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Lasix is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.