Generic Spiriva (Tiotropium Bromide)
Spiriva is an anticholinergic agent, it widens breathing passages and is used treat breathing difficulties caused by chronic obstructive pulmonary disease.
Per Inhalers
9 mcg x 1 inhaler
Next orders 10% discount
9 mcg x 3 inhalers
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9 mcg x 6 inhalers
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Product Description

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Common use

Spiriva is a specific antagonist of muscarinic receptors with longterm action. It reversibly blocks receptors of M3 type in respiratory track which results in relaxation of smooth muscles of the bronchial tree. High affinity of the receptors and slow release of the inhibitor from the complex with M3 receptor stipulates prolonged local action of Tiovais. Bronholitic effect of the drug results of local action, dose and persisted for at least 24 hours. Effects of Spiriva depend on the dose and continues for 24 hours. The medication is used to treat bronchial spasms (wheezing) caused by chronic obstructive pulmonary disease, chronic bronchitis and emphysema.

Dosage and direction

Spiriva comes as capsules with powder for inhalations with the HandiHaler inhalation device. Use the medication about the same time each day.


Cautiousness is needed in treatment of patients with narrow-angle glaucoma, urination disorders caused by prostatic hypertrophy or obstruction of the bladder neck. Tiovais cannto be used for urgent blockage of a bronchial spasm. Avoid getting of the medication in eyes. Monitoring on a regular basis is needed in the patients with moderate and severe renal failure treated by Tiovais and medications which excreted by the kidneys. Inhaled medications may cause paradoxical bronchospasm and other reactions of such kind. Avoid administration of the medication if you are pregnant or breastfeeding.


Spiriva cannot be administered to the patients with hypersensitivity to the medication, atropine and its derivates (ipratropium and oxytropine). Use in adolescents under 18 years of age is not researched.

Possible side effects

Most common side effects include local reactions such as dry mouth, throat pain, coughing, paradoxical bronchospasm. Changes in accommodation if the medication got into the eyes. Allergic reactions (rash, swelling) are possible. In rare were observed cases short heart beat, acute glaucoma, difficulty urination in men with prostatic hypertrophy, constipation.

Drug interactions

Concomitant use of Spiriva with other anticholinergetic medications is not recommended.

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your doses at about the same time each day to avoid missing a dose.


It was not reported about overdose if Spiriva was used in therapeutic doses. In case of considerable exceeding of the recommended dose symptoms associated with anticholinergetic properties of the medication are observed: reversible changes in accommodation, dry mouth. Acute poisoning is not likely due to low biological availability of the medication used as inhalations.


Store at room temperature away from moisture, sunlight, kids and pets in a tight container.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Lasix work and what pharmaceutical group does it belong to?

Lasix is a diuretic agent. Lasix causes a short term diuresis. Lasix action mechanism is associated with the reabsorbtion block of chloride and sodium ions in the Henle's loop.Lasix works by increasing excretion of K+, Ca2+, Mg2+ out of the organism. Hypotensive effect of the medication is associated with increased elimination of sodium and water.

Which conditions are treated with Lasix?

Lasix is used for the treatment of the following conditions:

  • Edema syndrome in chronic cardiac failure(II - III stage)
  • Cirrhosis
  • Kidney diseases
  • Cerebral edema
  • Hypertensive crisis
  • Hypertension
  • High calcium blood level

What should a patient know before using Lasix?

The Lasix should not be used in cases of:

  • Hypersensitivity
  • Severe renal failure
  • Acute liver failure
  • Ankylurethria
  • Acute glomerulonephritis
  • Hyperglycemic coma
  • Hyperuricemia
  • Arthragra
  • Decompensated mitral or aortal stenosis
  • Hypotension
  • Acute myocardial infarction
  • Pancreatitis
  • Digitalis intoxication

The drug should be used with caution in the following conditions:

  • Prostatic Hyperplasia
  • Systemic lupus erythematosus
  • Diabetes
  • Pregnancy
  • Breastfeeding

Which adverse effects may manifest when using the medication?

The side effects of Lasix include:

  • Cardiovascular system: hypotension, postural hypotension, collapse, tachycardia, arrhythmia, volume of blood circulation decrease.
  • Central nervous system: dizziness, headache, myasthenia, cramp in leg, paresthesia, apathy, adynamia, weakness, drowsiness,
  • Sense organs: vision and hearing disorders.
  • Gastrointestinal tract: appetite reduce, xerostomia, nausea, vomiting, constipations and diarrhea, pancreatitis.
  • Urinary system: oliguria, acute retention of urine, interstitial nephritis, erythrocyturia, decrease of sexual potency.
  • Allergic reactions: purpura, urticaria fever, exfoliative dermatitis, vasculitis, skin rash, shakes, fever.
  • Hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis, anemotrophy.
  • Water-electrolyte balance: hypovolemia, anhydration, hypokalemia, hyponatremia, hypomagnesemia, metabolic alkalosis.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Lasix?

The drug is affected by the following:

  • Immunodepresants
  • Aminoglycosides
  • Antimicrobial agents
  • Diuretics
  • Antineoplastics
  • Antimycotics
  • Antiulcer agents
  • Bronchodilating agents
  • Hypotensive preparations
  • Glucocorticosteroids
  • Cardiac glycosides

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Lasix is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.