Generic Sovaldi (Sofosbuvir)
Sovaldi
Generic Sovaldi (Sofosbuvir) is an antiviral medication that prevents hepatitis C virus (HCV) from multiplying in your body. With Generic Sovaldi, there’s hope that you can put “Hep C” behind you. You may be able to stop thinking about your disease, take the next step, and set a new course.
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400 mg x 28 pills
$1 154.90
$41.25
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400 mg x 56 pills
$1 924.99
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Product Description

Information: Sovaldi

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Sovaldi Nizoral
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The following lists contain some of the key side effects that may occur while Sovakdi Sovaldi. Sovaldi is indicated for use in adults without cirrhosis or Sovald compensated cirrhosis, and with the following types of hepatitis C virus HCV :. Some Sovaldii opt to travel to countries where treatment is cheaper. Ribavirin may also cause other serious side effects, including: Sovaldk blood disorders severe allergic reaction lung Sovaldi, such as Sovakdi decreased growth in children If you need to take ribavirin, talk with your doctor about the risks and benefits of using this drug. Sovaldi is also approved for use in children ages 3 years and older with HCV type 2 or 3. Once the virus can no longer multiply, it dies and your body can clear the infection. In Spain, the authorities have always covered up their agreement with the lab. All our news, direct to your mailing list Subscribe. Sovaldi was also studied in people with type 3 HCV. Drugs for Neglected Diseases Initiative. The price is CHF 16, Epclusa is not approved for use in children. Drug forms and strengths Sovaldi comes as mg and mg tablets. April Inhibiting this enzyme blocks replication of HCV, which eventually leads to elimination of the virus. In other cases, we use the price that countries pay for reimbursements, or official press releases. We need your support Civio spotlights goverment actions and exposes wrongdoing to spur reforms. Sofosbuvir is available by prescription in European Union countries to treat all genotypes of hepatitis C. More information about our republishing terms. Gilead's lawyers moved the Delhi high Court against this decision. Those who cannot use interferon can take sofosbuvir plus ribavirin alone for 24 weeks. As with all negotiations of this type, the pharmaceutical companies claim to adjust their prices according to the wealth of each country. Sovaldi contains the active substance sofosbuvir. To find current prices for Sovvaldi Sovaldi your Soavldi, check out GoodRx. Submit a letter to the editor Sivaldi write to letters theatlantic. Sovaldi comes as mg and mg tablets. Sofosbuvir can be used by Sobaldi being treated for hepatitis C for the first time known as 'treatment-naive' and for retreatment of people who were not cured with previous interferon-based therapy known as 'treatment-experienced'. Globally about million people have hepatitis C, which gradually destroys the liver. Will I need to use this drug long term? It also comes as pellets, which can be sprinkled on food and taken by mouth. Changes since initial authorisation of medicine List item. For children who weigh 17 kilograms about 37 pounds to less than 35 kilograms about 77 poundsthe typical dosage is mg each day. FDA approved the use of daclatasvir in combination with sofosbuvir for patients with genotype 3 chronic hepatitis C infection. These lists do not include all possible side effects. However, if your warfarin level gets too low, the drug may not work to properly thin your blood. Archived from the original on 10 February And brand-name Epclusa costs less than Sovaldi costs. Sovaldi can only be obtained with a prescription and treatment should be started and monitored by a doctor experienced in the management of patients with chronic hepatitis C.

Common use
The active ingredient present in Generic Sovaldi is Sofosbuvir – 400 mg.
Sofosbuvir is a nucleotide analog used in combination with other drugs for the treatment of hepatitis C virus (HCV) infection. Sofosbuvir is used for the treatment of chronic hepatitis C, genotypes 1, 2, 3, and 4, in combination with pegylated interferon and ribavirin, or with ribavirin alone. It is also used in combination with the viral NS5a inhibitor ledipasvir in an interferon-free combination for the treatment of genotype 1 hepatitis C infection. Sofosbuvir is also used in HCV patients with an HIV coinfection. The treatment is based on a number of clinical trials, for example the ELECTRON trial which showed that a dual interferon-free regimen of sofosbuvir plus ribavirin produced a 24-week post-treatment sustained virological response (SVR24) rate of 100% for previously untreated patients with HCV genotypes 2 or 3.
It is not known if sofosbuvir is safe and effective in children under 18 years of age.

Dosage and direction
Usual Adult Dose for Chronic Hepatitis C is 400 mg orally once a day
Recommended Regimens and Duration of Therapy:
-Genotype 1 or 4 chronic hepatitis C (CHC): Sofosbuvir, peginterferon alfa, and ribavirin for 12 weeks
-Genotype 2 CHC: Sofosbuvir and ribavirin for 12 weeks
-Genotype 3 CHC: Sofosbuvir and ribavirin for 24 weeks
-Hepatocellular carcinoma awaiting liver transplantation: Sofosbuvir and ribavirin for up to 48 weeks or until liver transplantation (whichever occurs first)
This drug should be used in combination with ribavirin or with pegylated interferon and ribavirin.
Efficacy was established in patients with HCV genotype 1, 2, 3, or 4 infection, including patients with hepatocellular carcinoma meeting Milan criteria (awaiting liver transplantation) and HCV/HIV-1 coinfected patients.
Sofosbuvir and ribavirin therapy for 24 weeks can be considered for patients with genotype 1 CHC who cannot use an interferon-based regimen; treatment decision should be guided by benefit/risk assessment for the individual patient.
Sofosbuvir and ribavirin therapy is recommended for patients with hepatocellular carcinoma awaiting liver transplantation to prevent posttransplant HCV reinfection.

Precautions
It is strongly recommended to consult your doctor or pharmacist before you start taking Generic Sovaldi and especially emphasize if you are allergic to this drug or if you take other medicines to treat Hepatitis C.
To make sure sofosbuvir is safe for you, tell your doctor if you have:
-liver problems other than hepatitis, or if you have had a liver transplant;
-kidney disease (or if you are on dialysis);
-HIV (human immunodeficiency virus);
-or if you have recently used a heart rhythm medicine called amiodarone (Cordarone, Pacerone).
Sofosbuvir is used in combination with ribavirin. Ribavirin can cause birth defects or death in an unborn baby. You may need to have a negative pregnancy test before using these medications together, and every month during your treatment. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using sofosbuvir with ribavirin.
If you are a man, do not use this drug combination if your sexual partner is pregnant.
It is not known whether sofosbuvir passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
Taking this medication will not prevent you from passing hepatitis C to other people. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HCV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.

Contraindications
Drinking alcohol while taking Generic Sovaldi can cause dangerous or unwanted side effects.
Grapefruit and grapefruit juice may interact with sofosbuvir and lead to unwanted side effects. Avoid the use of grapefruit products while taking Generic Sovaldi.

Possible side effect
Call your doctor at once if you have: pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating; or fever, swollen gums, painful mouth sores, skin sores, cold or flu symptoms, cough.
Common side effects may include: headache, tired feeling; mild itching; nausea; sleep problems.
This is not a complete list of side effects and others may occur. Call your doctor for or pharmacist medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Drug interaction
When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of these medicines: Amiodarone; Carbamazepine; Eliglustat; Fosphenytoin; Oxcarbazepine; Phenobarbital; Phenytoin; Primidone; Rifabutin; Rifampin; Rifapentine; St John's Wort; Tipranavir; Ulipristal

Missed dose
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. Do not take more than 400 milligrams of sofosbuvir in one day.

Overdose
If you think you have used too much of Sovaldi - seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage
Store this medicine at 25°C (77°F), with excursions permitted between 15°C and 30°C (59°F and 86°F) away from moisture and heat. Keep all drugs out of the reach children and pets.

 

Disclaimer
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Lasix work and what pharmaceutical group does it belong to?

Lasix is a diuretic agent. Lasix causes a short term diuresis. Lasix action mechanism is associated with the reabsorbtion block of chloride and sodium ions in the Henle's loop.Lasix works by increasing excretion of K+, Ca2+, Mg2+ out of the organism. Hypotensive effect of the medication is associated with increased elimination of sodium and water.

Which conditions are treated with Lasix?

Lasix is used for the treatment of the following conditions:

  • Edema syndrome in chronic cardiac failure(II - III stage)
  • Cirrhosis
  • Kidney diseases
  • Cerebral edema
  • Hypertensive crisis
  • Hypertension
  • High calcium blood level

What should a patient know before using Lasix?

The Lasix should not be used in cases of:

  • Hypersensitivity
  • Severe renal failure
  • Acute liver failure
  • Ankylurethria
  • Acute glomerulonephritis
  • Hyperglycemic coma
  • Hyperuricemia
  • Arthragra
  • Decompensated mitral or aortal stenosis
  • Hypotension
  • Acute myocardial infarction
  • Pancreatitis
  • Digitalis intoxication

The drug should be used with caution in the following conditions:

  • Prostatic Hyperplasia
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  • Diabetes
  • Pregnancy
  • Breastfeeding

Which adverse effects may manifest when using the medication?

The side effects of Lasix include:

  • Cardiovascular system: hypotension, postural hypotension, collapse, tachycardia, arrhythmia, volume of blood circulation decrease.
  • Central nervous system: dizziness, headache, myasthenia, cramp in leg, paresthesia, apathy, adynamia, weakness, drowsiness,
  • Sense organs: vision and hearing disorders.
  • Gastrointestinal tract: appetite reduce, xerostomia, nausea, vomiting, constipations and diarrhea, pancreatitis.
  • Urinary system: oliguria, acute retention of urine, interstitial nephritis, erythrocyturia, decrease of sexual potency.
  • Allergic reactions: purpura, urticaria fever, exfoliative dermatitis, vasculitis, skin rash, shakes, fever.
  • Hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis, anemotrophy.
  • Water-electrolyte balance: hypovolemia, anhydration, hypokalemia, hyponatremia, hypomagnesemia, metabolic alkalosis.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Lasix?

The drug is affected by the following:

  • Immunodepresants
  • Aminoglycosides
  • Antimicrobial agents
  • Diuretics
  • Antineoplastics
  • Antimycotics
  • Antiulcer agents
  • Bronchodilating agents
  • Hypotensive preparations
  • Glucocorticosteroids
  • Cardiac glycosides
  • NSAID

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Lasix is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.