Generic Loxitane (Loxapine)
Loxitane belongs to a class of medications so called tricyclic antipsycotics. It is not know exactly how this medication works. It is used to treat schizophrenia.
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Common use

Loxitane belongs to a class of medications so called tricyclic antipsycotics. It is not know exactly how this medication works. It is used to treat schizophrenia.

Dosage and directions


Tell you doctor about all conditions you have and especially: if you have any allergies, you have a history of other mental problems, heart problems, glaucoma, difficulty urinating or risk factors for difficult urination, Parkinson disease, breast cancer, liver problems, brain growths or cancer, a stomach blockage, or seizures; you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement; you are pregnant, planning to become pregnant, or are breast-feeding; you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement; you are dependent on alcohol or drink large amounts of alcohol regularly; you are very ill or weakened.


You should not use Loxitane if you have allergy to it or to other similar medications; you take sodium oxybate, you have severe central nervous system depression, you are in coma or have been sedated.

Possible side effects

The most common side effects are constipation, blurred vision, dizziness, drowsiness, dry mouth, headache, nausea, stuffy nose, trouble sleeping, omiting, weight gain or loss.

Severe side effects incude Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; altered mental abilities, including lack of response to your surroundings; chills or persistent sore throat; confusion; dark urine; decreased urination; fainting or faintness; fast or irregular heartbeat; hyperactivity; increased saliva production; increased thirst; involuntary, uncontrolled muscle movements; menstrual changes; mental or mood changes; muscle twitching; numbness or tingling of the skin; restlessness; seizures; shortness of breath; severe constipation; slurred speech; staggering or shuffling gait; stiff or rigid muscles; sweating; tremor; unexplained fever; vision changes; yellowing of the eyes or skin.

Seek medical attention if one of the listed above symptoms occurs.

Drug interaction

Tell your doctor if you take the folllowing medicines:

barbiturates (eg, phenobarbital), narcotics (eg, codeine), or sodium oxybate ( GHB) because the risk of side effects, such as severe drowsiness, may be increased ;anticholinergics (eg, trihexyphenidyl) because side effects of Loxitane may be increased; benzodiazepines (eg, lorazepam) because side effects may be increased by Loxitane.

Missed dose

If you miss a dose of Loxitane, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.


Symptoms of overdose include decreased urination; difficulty breathing; involuntary, uncontrolled muscle movements; loss of consciousness; seizures; severe or persistent dizziness. Seek medical attention immediately if you overdosed the medicine.


Store Loxitane at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Loxitane out of the reach of children and away from pets.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Lasix work and what pharmaceutical group does it belong to?

Lasix is a diuretic agent. Lasix causes a short term diuresis. Lasix action mechanism is associated with the reabsorbtion block of chloride and sodium ions in the Henle's loop.Lasix works by increasing excretion of K+, Ca2+, Mg2+ out of the organism. Hypotensive effect of the medication is associated with increased elimination of sodium and water.

Which conditions are treated with Lasix?

Lasix is used for the treatment of the following conditions:

  • Edema syndrome in chronic cardiac failure(II - III stage)
  • Cirrhosis
  • Kidney diseases
  • Cerebral edema
  • Hypertensive crisis
  • Hypertension
  • High calcium blood level

What should a patient know before using Lasix?

The Lasix should not be used in cases of:

  • Hypersensitivity
  • Severe renal failure
  • Acute liver failure
  • Ankylurethria
  • Acute glomerulonephritis
  • Hyperglycemic coma
  • Hyperuricemia
  • Arthragra
  • Decompensated mitral or aortal stenosis
  • Hypotension
  • Acute myocardial infarction
  • Pancreatitis
  • Digitalis intoxication

The drug should be used with caution in the following conditions:

  • Prostatic Hyperplasia
  • Systemic lupus erythematosus
  • Diabetes
  • Pregnancy
  • Breastfeeding

Which adverse effects may manifest when using the medication?

The side effects of Lasix include:

  • Cardiovascular system: hypotension, postural hypotension, collapse, tachycardia, arrhythmia, volume of blood circulation decrease.
  • Central nervous system: dizziness, headache, myasthenia, cramp in leg, paresthesia, apathy, adynamia, weakness, drowsiness,
  • Sense organs: vision and hearing disorders.
  • Gastrointestinal tract: appetite reduce, xerostomia, nausea, vomiting, constipations and diarrhea, pancreatitis.
  • Urinary system: oliguria, acute retention of urine, interstitial nephritis, erythrocyturia, decrease of sexual potency.
  • Allergic reactions: purpura, urticaria fever, exfoliative dermatitis, vasculitis, skin rash, shakes, fever.
  • Hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis, anemotrophy.
  • Water-electrolyte balance: hypovolemia, anhydration, hypokalemia, hyponatremia, hypomagnesemia, metabolic alkalosis.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Lasix?

The drug is affected by the following:

  • Immunodepresants
  • Aminoglycosides
  • Antimicrobial agents
  • Diuretics
  • Antineoplastics
  • Antimycotics
  • Antiulcer agents
  • Bronchodilating agents
  • Hypotensive preparations
  • Glucocorticosteroids
  • Cardiac glycosides

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Lasix is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.