Generic Lopressor (Metoprolol)
Lopressor is a selective β1 receptor blocker prescribed in treatment of hypertension, angina, heart arrhythmia.
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Product Description

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Common use

Lopressor acts mostly blocking beta-adrenoreceptors of the heart and is used to treat hypertension, chest pain (angina), abnormal rhythms of the heart, to treat and prevent myocardial infarction. This medication influences autonomic nervous system which stipulates increased heart rate by blocking its receptors and thus reducing abnormally rapid heart rhythms. It also diminishes myocard irritability, cardiac output and causes other effects.

Dosage and direction

This medication should be taken with food or just after a meal. Do not chew, squash or break a tablet, drink a glass of water with it. Dosage depends on the treated disease and may vary between 100-450 mg daily. Your individual dosage should be prescribed by your physician. Aged patients are recommended to start from 50 mg daily dose. Kidnely failire does not require a dosage correction while liver failure requires usage of other beta-adrenoblockers which are not destructed in liver.


Avoid drinking alcohol as its interaction with Lopressor increases drowsiness and dizziness.


Hypersensitivity to the components of the medication, acute or chronic heart failure, arterial hypotention, congestive heart failure, asthma or other breathing problems, diabetes, disorders of perepherial blood circulation, pregnancy, breast-feeding, depression, liver or kidney disease, a thyroid disorder, or myasthenia gravis.

Possible side effect

At the background of common tolerance to the medication among side effects are noticed abdominal cramps, fatigue, insomnia, nausea, depression, memory loss, fever, impotence, lightheadedness, slow heart rate, low blood pressure, cold extremities, sore throat, diarrhea, constipation, and shortness of breath or wheezing.

Drug interaction

Attention should be paid to intake of calcium channel blockers and digoxin (Lanoxin) which are known by dangerous lowering of blood pressure and heart rate being administered together with Lopressor.

Lopressor also is able to mask the early symptoms of low blood sugar and should be used with caution in patients suffering from diabetes.

Missed dose

Take the forgotten dose as soon as you remember. If your next dose is less than 4 hours away, skip it and return to your schedule. Do not try to compensate a missed dose by taking an extra one.


In case such symptoms of Lopressor are noticed: uneven heartbeats, shortness of breath, dizziness, weakness or fainting, bluish-colored fingernails, seek for immediate medical help.


Store between 15-30 C (59-86 F). Protect this medication away from moisture and sunlight in tight, light-resistant container.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Lasix work and what pharmaceutical group does it belong to?

Lasix is a diuretic agent. Lasix causes a short term diuresis. Lasix action mechanism is associated with the reabsorbtion block of chloride and sodium ions in the Henle's loop.Lasix works by increasing excretion of K+, Ca2+, Mg2+ out of the organism. Hypotensive effect of the medication is associated with increased elimination of sodium and water.

Which conditions are treated with Lasix?

Lasix is used for the treatment of the following conditions:

  • Edema syndrome in chronic cardiac failure(II - III stage)
  • Cirrhosis
  • Kidney diseases
  • Cerebral edema
  • Hypertensive crisis
  • Hypertension
  • High calcium blood level

What should a patient know before using Lasix?

The Lasix should not be used in cases of:

  • Hypersensitivity
  • Severe renal failure
  • Acute liver failure
  • Ankylurethria
  • Acute glomerulonephritis
  • Hyperglycemic coma
  • Hyperuricemia
  • Arthragra
  • Decompensated mitral or aortal stenosis
  • Hypotension
  • Acute myocardial infarction
  • Pancreatitis
  • Digitalis intoxication

The drug should be used with caution in the following conditions:

  • Prostatic Hyperplasia
  • Systemic lupus erythematosus
  • Diabetes
  • Pregnancy
  • Breastfeeding

Which adverse effects may manifest when using the medication?

The side effects of Lasix include:

  • Cardiovascular system: hypotension, postural hypotension, collapse, tachycardia, arrhythmia, volume of blood circulation decrease.
  • Central nervous system: dizziness, headache, myasthenia, cramp in leg, paresthesia, apathy, adynamia, weakness, drowsiness,
  • Sense organs: vision and hearing disorders.
  • Gastrointestinal tract: appetite reduce, xerostomia, nausea, vomiting, constipations and diarrhea, pancreatitis.
  • Urinary system: oliguria, acute retention of urine, interstitial nephritis, erythrocyturia, decrease of sexual potency.
  • Allergic reactions: purpura, urticaria fever, exfoliative dermatitis, vasculitis, skin rash, shakes, fever.
  • Hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis, anemotrophy.
  • Water-electrolyte balance: hypovolemia, anhydration, hypokalemia, hyponatremia, hypomagnesemia, metabolic alkalosis.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Lasix?

The drug is affected by the following:

  • Immunodepresants
  • Aminoglycosides
  • Antimicrobial agents
  • Diuretics
  • Antineoplastics
  • Antimycotics
  • Antiulcer agents
  • Bronchodilating agents
  • Hypotensive preparations
  • Glucocorticosteroids
  • Cardiac glycosides

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Lasix is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.