Generic Keflex (Cephalexin)
Keflex is a cephalosporin antibiotic used in treatment of respiratory infections and ear infections.
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Product Description

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Common use

Keflex is attributed as antibiotic of cephalosporins group which act against bacteria preventing formation of their cell walls. It is enough resistant to penicillinases of gram positive microorganims but can be destroyed by beta-lactamases of gram negative ones. It shows broad spectrum activity against gram positive microogranisms such as Staphylococcus, Staphylococcus epidermidis; Streptococcus, Corynebacterium diphtheriae, Clostridium, Actinomyces israelii, Bacillus anthracis, gram negative microorganisms like Escherichia coli, Klebsiella, Proteus mirabilis, Neisseria gonorrhoeae, Neisseria meningitidis, Shigella, Salmonella. Common infections that are treated with Keflex include infections of the middle ear, tonsils, throat, larynx (laryngitis), bronchi (bronchitis) and pneumonia as well as in urinary tract, skin, and bones.

Dosage and directions

The dose of Keflex for adults is 1 to 4 grams in divided doses. The interval between doses may be 6 or 12 hours depending on the infection.


Before using Keflex, tell your doctor if you are allergic to any drugs (especially penicillins), have kidney or liver disease, a stomach or intestinal disorder such as colitis, and diabetes.


Hypersensitivity to Keflex, cephalosporins (Ceclor, Duricef, Omnicef, Spectracef, Suprax, Cefzil, Fortaz, Ceftin) and beta-lactamase antibiotics. Cautiousness should be exercised in patients with kidney disorder, pseudomembranous colitis, pregnancy, breastfeeding and babies younger than 6 month.

Possible side effect

Most common side effects may include signs of allergy (hives, rash, swelling of face and tongue), seizure, fever, sore throat, and headache with a severe blistering, peeling, and red skin rash, pale or yellowed skin, dark colored urine, fever, hallucinations, confusion or weakness, easy bruising or bleeding, unusual weakness, confusion, agitation, decreased or absent urination. In case of serious and persistent side effects listed above seek for immediate medical help.

Drug interaction

Inform your doctor about all medications you take and especially about live vaccines, probenecid. Keflex may decrease the effectiveness of combination-type contraceptive pills. This medication is able to show false positive results with certain diabetic urine testing products. Keflex increases effects of indirect anticoagulants, polphenilbutazone, furocemide. Salicylates and indomethacin slow excretion of cephalolexin by kidneys. Medications decreasing secretion in renal tubules increase concentration of the medication blood serum and slow down its excretion.

Missed dose

If you missed a dose take it as soon as you remember. If it almost time of your next dose just skip it and return to your regular schedule. Never double dose this medication.


In case of serious and persistent symptoms of nausea, vomiting, stomach pain, diarrhea, and blood in your urine consult your doctor about medical attention.


Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Lasix work and what pharmaceutical group does it belong to?

Lasix is a diuretic agent. Lasix causes a short term diuresis. Lasix action mechanism is associated with the reabsorbtion block of chloride and sodium ions in the Henle's loop.Lasix works by increasing excretion of K+, Ca2+, Mg2+ out of the organism. Hypotensive effect of the medication is associated with increased elimination of sodium and water.

Which conditions are treated with Lasix?

Lasix is used for the treatment of the following conditions:

  • Edema syndrome in chronic cardiac failure(II - III stage)
  • Cirrhosis
  • Kidney diseases
  • Cerebral edema
  • Hypertensive crisis
  • Hypertension
  • High calcium blood level

What should a patient know before using Lasix?

The Lasix should not be used in cases of:

  • Hypersensitivity
  • Severe renal failure
  • Acute liver failure
  • Ankylurethria
  • Acute glomerulonephritis
  • Hyperglycemic coma
  • Hyperuricemia
  • Arthragra
  • Decompensated mitral or aortal stenosis
  • Hypotension
  • Acute myocardial infarction
  • Pancreatitis
  • Digitalis intoxication

The drug should be used with caution in the following conditions:

  • Prostatic Hyperplasia
  • Systemic lupus erythematosus
  • Diabetes
  • Pregnancy
  • Breastfeeding

Which adverse effects may manifest when using the medication?

The side effects of Lasix include:

  • Cardiovascular system: hypotension, postural hypotension, collapse, tachycardia, arrhythmia, volume of blood circulation decrease.
  • Central nervous system: dizziness, headache, myasthenia, cramp in leg, paresthesia, apathy, adynamia, weakness, drowsiness,
  • Sense organs: vision and hearing disorders.
  • Gastrointestinal tract: appetite reduce, xerostomia, nausea, vomiting, constipations and diarrhea, pancreatitis.
  • Urinary system: oliguria, acute retention of urine, interstitial nephritis, erythrocyturia, decrease of sexual potency.
  • Allergic reactions: purpura, urticaria fever, exfoliative dermatitis, vasculitis, skin rash, shakes, fever.
  • Hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis, anemotrophy.
  • Water-electrolyte balance: hypovolemia, anhydration, hypokalemia, hyponatremia, hypomagnesemia, metabolic alkalosis.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Lasix?

The drug is affected by the following:

  • Immunodepresants
  • Aminoglycosides
  • Antimicrobial agents
  • Diuretics
  • Antineoplastics
  • Antimycotics
  • Antiulcer agents
  • Bronchodilating agents
  • Hypotensive preparations
  • Glucocorticosteroids
  • Cardiac glycosides

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Lasix is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.