Generic Imodium (Loperamide)
Imodium is an antidiarrheal drug which slows the rhythm of digestion and absorption of fluid in the small intestines.
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Product Description

Imodium - simply does

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Common use

Imodium is an antidiarrheal medication. It binds opioid receptors in the wall of intestine, inhibits release of acetylcholine and prostaglandins hereby reducing peristalsis, increases time needed for the food to pass through intestines. Imodium increases tone of the anal sphincter, reducing stool incontinence and urge to defecate. Imodium is used to treat diarrhea, to reduce the amount of stool in patients with ileostomy (re-routing of the bowel is brought out by a surgical opening through in the stomach).

Dosage and directions

The drug is administered for oral intake. To treat acute diarrhea in adults and elderly patients a prescribed initial dose is 4 mg, decreased to 2 mg in the future after each act of defecation in the case of loose stool. Initial dose of 2 mg is recommended for children older than 6 y.o. which maybe diminished to 2 mg after each act of defecation in the case of loose stool. Tablets of Imodium are rather fragile so do not press them through the foil. Chew the tablets before to swallow them. Do not take Imodium more than 3 times in 24 hours.


Do not use Imodium if you are allergic to loperamide, or if you have bloody or mucous stools or ones of black and tarry color, or if you have diarrhea caused by antibiotics. Try to drink extra water and keep diet while you are taking this medication to avoid dehydration. It may take up to 48 hours of taking Imodium to improve your condition. Notify your doctor if you have lier failure, AIDS.


Acute dysentery and other gastrointestinal infections (caused by Salmonella, Shigella, Campylobacter), ileus , diverticulosis, acute ulcerative colitis, pseudomembranous enterocolitis (diarrhea caused by taking antibiotics), first trimester of pregnancy, lactation, infancy (younger than 6 y.o.), hypersensitivity to loperamide and/or other components of the drug.

Possible side effect

Side effects may include symptoms of allergy like hives, rash, swelling of face and tongue, dizziness, drowsiness, constipation, stomach pain or bloating, dry mouth, ongoing or worsening diarrhea, watery or bloody diarrhea, excessive gas, nausea, vomiting fever, headache, severe blistering. Stop using this medication and call your doctor at once if you experience the listed symptoms.

Drug interaction

Inform your doctor if you are takeing saquinavir (Invirase), quinidine, ritonavir. The two last medications are both P-glycoprotein inhibitors and their co-administration with Imodium may result in increase in Imodium plasma levels. Levels of saquinavir are decreased by concomitant intake of Imodium.

Missed dose

If you missed a dose take the medication as soon as you remember. If it is almost time of your next dose just skip its intake and return to your regular schedule. Though this medication may not need to be on a dosing schedule and take it once or twice when needed.


Overdose symptoms are dizziness, drowsiness, unusually rare and little urination, severe stomach cramps, bloating, and vomiting. You may need immediate medical help so inform your doctor if you believe that took too much of this medication.


Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Lasix work and what pharmaceutical group does it belong to?

Lasix is a diuretic agent. Lasix causes a short term diuresis. Lasix action mechanism is associated with the reabsorbtion block of chloride and sodium ions in the Henle's loop.Lasix works by increasing excretion of K+, Ca2+, Mg2+ out of the organism. Hypotensive effect of the medication is associated with increased elimination of sodium and water.

Which conditions are treated with Lasix?

Lasix is used for the treatment of the following conditions:

  • Edema syndrome in chronic cardiac failure(II - III stage)
  • Cirrhosis
  • Kidney diseases
  • Cerebral edema
  • Hypertensive crisis
  • Hypertension
  • High calcium blood level

What should a patient know before using Lasix?

The Lasix should not be used in cases of:

  • Hypersensitivity
  • Severe renal failure
  • Acute liver failure
  • Ankylurethria
  • Acute glomerulonephritis
  • Hyperglycemic coma
  • Hyperuricemia
  • Arthragra
  • Decompensated mitral or aortal stenosis
  • Hypotension
  • Acute myocardial infarction
  • Pancreatitis
  • Digitalis intoxication

The drug should be used with caution in the following conditions:

  • Prostatic Hyperplasia
  • Systemic lupus erythematosus
  • Diabetes
  • Pregnancy
  • Breastfeeding

Which adverse effects may manifest when using the medication?

The side effects of Lasix include:

  • Cardiovascular system: hypotension, postural hypotension, collapse, tachycardia, arrhythmia, volume of blood circulation decrease.
  • Central nervous system: dizziness, headache, myasthenia, cramp in leg, paresthesia, apathy, adynamia, weakness, drowsiness,
  • Sense organs: vision and hearing disorders.
  • Gastrointestinal tract: appetite reduce, xerostomia, nausea, vomiting, constipations and diarrhea, pancreatitis.
  • Urinary system: oliguria, acute retention of urine, interstitial nephritis, erythrocyturia, decrease of sexual potency.
  • Allergic reactions: purpura, urticaria fever, exfoliative dermatitis, vasculitis, skin rash, shakes, fever.
  • Hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis, anemotrophy.
  • Water-electrolyte balance: hypovolemia, anhydration, hypokalemia, hyponatremia, hypomagnesemia, metabolic alkalosis.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Lasix?

The drug is affected by the following:

  • Immunodepresants
  • Aminoglycosides
  • Antimicrobial agents
  • Diuretics
  • Antineoplastics
  • Antimycotics
  • Antiulcer agents
  • Bronchodilating agents
  • Hypotensive preparations
  • Glucocorticosteroids
  • Cardiac glycosides

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Lasix is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.