Generic Geodon (Ziprasidone)
Geodon
Geodon is an atypical antipsychotic used in treatment of schizophrenia and the manic symptoms of bipolar disorder.
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Product Description

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Common use

Geodon is used to treat schizophrenia and the manic episodes of bipolar disorder. It possesses high affinity to dopamine D2-receptors and more significant affinity to serotonin 5-HT2A-receptors. It is supposed that the medication blocks serotonin and dopamine receptors and inhibits the re-uptake of serotonin and norepinephrine in the brain and this way shows its anti-psychotic activity. Geodon is used to treat psychotic disorders, schizophrenia, and affective disorders. Due to its potentially serious side effects it is administered only if other medications have proved inadequate.



Dosage and direction

The recommended dose for adults is 40 mg two times a day and should be corrected for each particular condition. Geodon is available in dosage of 20 mg, 40 mg, and 80 mg. Maximal dose is 160 mg a day. Take it orally with a meal. Dose correction is required in patients with with hepatic impairments.



Precautions

Cautiousness is required when the medication is administered in patients with severe hepatic failure, bradicardia, electrolyte disorders. This medication causes drowsiness so certain cautiousness is required while driving and operating a machinery.



Contraindications

Geodon cannot be used in pregnant and breastfeeding women excluding cases when supposed benefit prevails over potential risk for the unborn baby. Patients hypersensitive to the medication cannot take it. Individuals with the extension of the QT interval (including congenital syndrome of extension of the QT interval ), recent acute myocardial infarction, decompensated heart failure, arrhythmia treated with administration of class IA and III antiarrhythmic drugs cannot be treated by Geodeon. Effects of the medication in the patients under 18 y.o. have not been studied.



Possible side effect

Side effects cannot be anticipated and if occur they are transient. Adverse reactions include: asthenia, accidental injury, headache, drowsiness, dizziness, tremor, anorexia, vomiting, cold symptoms, upper respiratory infection, stuffy and runny nose, nausea, constipation, diarrhea, indigestion, cough, dry mouth, fatigue, involuntary muscle contractions, muscle aches, muscle tightness, rapid heartbeat, rash, skin fungus, twitching, vision problems, weakness.



Drug interaction

Thioridazine (Mellaril), moxifloxacin (Avelox), pimozide (Orap), quinidine (Quinidex), dofetilide (Tikosyn), sotalol (Betapace), and sparfloxacin (Zagam) should not be taken with Geodon due to increased risk of serious disturbances in the heart rhythm. Carbamazepine (Tegretol) diminish effects of Geodon while Ketoconazole (Nizoral) acts just the opposite as well as itraconazole (Sporanox), fluconazole (Diflucan), nefazodone (Serzone), verapamil (Calan, Isoptin, Verelan), erythromycin, clarithromycin (Biaxin), and diltiazem (Cardizem, Tiazac, Dilacor).



Missed dose

Take the missed dose as soon as you remember. If it is almost time of your next dose just skip the missed dose and return to your schedule. Do not double dose this medication to make up the missed dose.



Overdose

Symptoms of overdose may include anxiety, drowsiness, tremors, slurred speech, and transient high blood pressure. Contact your doctor immediately in case of suspected overdose.



Storage

Store at room temperature, 15-30 C (59-86 F) away from sunlight, moisture, children and pets.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Lasix work and what pharmaceutical group does it belong to?

Lasix is a diuretic agent. Lasix causes a short term diuresis. Lasix action mechanism is associated with the reabsorbtion block of chloride and sodium ions in the Henle's loop.Lasix works by increasing excretion of K+, Ca2+, Mg2+ out of the organism. Hypotensive effect of the medication is associated with increased elimination of sodium and water.

Which conditions are treated with Lasix?

Lasix is used for the treatment of the following conditions:

  • Edema syndrome in chronic cardiac failure(II - III stage)
  • Cirrhosis
  • Kidney diseases
  • Cerebral edema
  • Hypertensive crisis
  • Hypertension
  • High calcium blood level

What should a patient know before using Lasix?

The Lasix should not be used in cases of:

  • Hypersensitivity
  • Severe renal failure
  • Acute liver failure
  • Ankylurethria
  • Acute glomerulonephritis
  • Hyperglycemic coma
  • Hyperuricemia
  • Arthragra
  • Decompensated mitral or aortal stenosis
  • Hypotension
  • Acute myocardial infarction
  • Pancreatitis
  • Digitalis intoxication

The drug should be used with caution in the following conditions:

  • Prostatic Hyperplasia
  • Systemic lupus erythematosus
  • Diabetes
  • Pregnancy
  • Breastfeeding

Which adverse effects may manifest when using the medication?

The side effects of Lasix include:

  • Cardiovascular system: hypotension, postural hypotension, collapse, tachycardia, arrhythmia, volume of blood circulation decrease.
  • Central nervous system: dizziness, headache, myasthenia, cramp in leg, paresthesia, apathy, adynamia, weakness, drowsiness,
  • Sense organs: vision and hearing disorders.
  • Gastrointestinal tract: appetite reduce, xerostomia, nausea, vomiting, constipations and diarrhea, pancreatitis.
  • Urinary system: oliguria, acute retention of urine, interstitial nephritis, erythrocyturia, decrease of sexual potency.
  • Allergic reactions: purpura, urticaria fever, exfoliative dermatitis, vasculitis, skin rash, shakes, fever.
  • Hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis, anemotrophy.
  • Water-electrolyte balance: hypovolemia, anhydration, hypokalemia, hyponatremia, hypomagnesemia, metabolic alkalosis.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Lasix?

The drug is affected by the following:

  • Immunodepresants
  • Aminoglycosides
  • Antimicrobial agents
  • Diuretics
  • Antineoplastics
  • Antimycotics
  • Antiulcer agents
  • Bronchodilating agents
  • Hypotensive preparations
  • Glucocorticosteroids
  • Cardiac glycosides
  • NSAID

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Lasix is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.