Generic Frumil (Amiloride)
Frumil
Frumil is a potent diuretic that is used for treatment of hypertension and swelling caused by heart failure and other conditions.
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Product Description

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Common use

Frumil (Amiloride, Hydrochlorothiazide, Midamor) is a diuretic combination used in the treatment of high blood pressure and congestive heart failure, edematous syndrome of various origin (including those which occur with chronic heart failure nephrotic syndrome, cirrhosis).



Dosage and direction

If you are treated for high blood pressure use of Frumil requires several weeks as it does not treat hypertension but just keeps it under control.



Precautions

If you are sick with diabetes, kidney or liver disease, drug allergies notify your doctor about your condition. Do not large amounts of food with high content of potassium such as bananas, baked potatoes, cantaloupe, avocado, raisins, cooked spinach. Alcohol may increase the effects of this drug and some of its side effects. Do not stand up from a lying position rapidly, just sit for a few minutes before rising. Frumil does not cause potassium loss from the body so there is no need in salt substitutes. Inform your doctor if you are plan pregnancy or are already pregnant.



Contraindications

Hypersensitivity, hyperpotassemia, severe kidney disorders, hepatic coma.



Possible side effect

This drug may cause dizziness or vision changes, dehydration (dry mouth) or thirst, vomit, nausea, headache hyperpotassemia. Seek for medical attention in case you experience muscle cramps, irregular heartbeat, tingling of the hands or feet, fatigue, breathing difficulties, difficulty urinating.



Drug interaction

Frumil may interact with such drugs: ACE inhibitors, barbiturates, cholestyramine, corticosteroids, insulin, cyclosporine, muscle relaxants such as tubocurarine, nonsteroidal anti-inflammatory drugs, other high blood pressure medications.



Missed dose

If you missed a dose take it as soon as you remember, but not if it is almost time of the next intake by your schedule. If so do not take the missed dose. Do not try to compensate a missed dose by taking an extra one.



Overdose

Seek emergency medical attention if you think you have taken too much of Frumil. There are not special signs of overdose for this medication except of dehydration.



Storage

Store at room temperature between 59-86 F (between 15-30 C), keep Frumil away from moisture and sunlight.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Lasix work and what pharmaceutical group does it belong to?

Lasix is a diuretic agent. Lasix causes a short term diuresis. Lasix action mechanism is associated with the reabsorbtion block of chloride and sodium ions in the Henle's loop.Lasix works by increasing excretion of K+, Ca2+, Mg2+ out of the organism. Hypotensive effect of the medication is associated with increased elimination of sodium and water.

Which conditions are treated with Lasix?

Lasix is used for the treatment of the following conditions:

  • Edema syndrome in chronic cardiac failure(II - III stage)
  • Cirrhosis
  • Kidney diseases
  • Cerebral edema
  • Hypertensive crisis
  • Hypertension
  • High calcium blood level

What should a patient know before using Lasix?

The Lasix should not be used in cases of:

  • Hypersensitivity
  • Severe renal failure
  • Acute liver failure
  • Ankylurethria
  • Acute glomerulonephritis
  • Hyperglycemic coma
  • Hyperuricemia
  • Arthragra
  • Decompensated mitral or aortal stenosis
  • Hypotension
  • Acute myocardial infarction
  • Pancreatitis
  • Digitalis intoxication

The drug should be used with caution in the following conditions:

  • Prostatic Hyperplasia
  • Systemic lupus erythematosus
  • Diabetes
  • Pregnancy
  • Breastfeeding

Which adverse effects may manifest when using the medication?

The side effects of Lasix include:

  • Cardiovascular system: hypotension, postural hypotension, collapse, tachycardia, arrhythmia, volume of blood circulation decrease.
  • Central nervous system: dizziness, headache, myasthenia, cramp in leg, paresthesia, apathy, adynamia, weakness, drowsiness,
  • Sense organs: vision and hearing disorders.
  • Gastrointestinal tract: appetite reduce, xerostomia, nausea, vomiting, constipations and diarrhea, pancreatitis.
  • Urinary system: oliguria, acute retention of urine, interstitial nephritis, erythrocyturia, decrease of sexual potency.
  • Allergic reactions: purpura, urticaria fever, exfoliative dermatitis, vasculitis, skin rash, shakes, fever.
  • Hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis, anemotrophy.
  • Water-electrolyte balance: hypovolemia, anhydration, hypokalemia, hyponatremia, hypomagnesemia, metabolic alkalosis.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Lasix?

The drug is affected by the following:

  • Immunodepresants
  • Aminoglycosides
  • Antimicrobial agents
  • Diuretics
  • Antineoplastics
  • Antimycotics
  • Antiulcer agents
  • Bronchodilating agents
  • Hypotensive preparations
  • Glucocorticosteroids
  • Cardiac glycosides
  • NSAID

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Lasix is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.