Feldene (Piroxicam)
Feldene is used to treat rheumatoid arthritis or osteoarthritis.
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Product Description

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Common use

Feldene is a non-steroidal anti-inflammatory drug, which used to treat rheumatoid arthritis or osteoarthritis. Feldene reduces hormones that cause inflammation and pain in the body.

Dosage and direction

Consult with your doctor before using. Use no more than was prescribed. Take it orally with food or milk. For osteoarthritis and rheumatoid arthritis the recommended dose is 20 milligrams (mg) once a day or 10 mg twice a day. Do not use this medication in children without doctor's permission.

Note: this instruction presented here just for review. It's very necessary to consult with your doctor before using. It help you to get best results.


If you have heart disease, or high blood pressure, or other conditions that cause fluid retention, use Feldene with caution. This medication can increase water retention and is not recommended for people with advanced kidney disease, also Feldene cause liver damage. Also medications such as Feldene may cause eye disturbances in some patients. If you develop visual problems, tell your eye doctor. Feldene can increase risk of serious stomach or bowel problems. If your health is poor, if you have a history of smoking or drinking alcohol, if you take corticosteroid medicines or "blood thinners", or if you take this medicine for a long period of time there is the risk of taking Feldene will be increased. Feldene should not be used during pregnancy, becoming pregnant or lactating without doctor's advice. Do not use Feldene before breast-feeding without doctor's advice.


Feldene is not allowed in people with active peptic ulcer, inflammatory gastrointestinal disorder, gastrointestinal bleeding or hypersensitive to Feldene, Aspirin, or similar drugs. Also if you have had asthma attacks caused by Aspirin or other drugs of this type, you should not take this medication. Do not use Feldene for the treatment of peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery.

Possible side effect

They may include all types of an allergic reaction. Also the most possible side effects include:

weakness, chest pain, shortness of breath, problems with vision or balance,slurred speech;

bloody, black, or tarry stools;

coughing up blood or vomit that looks like coffee grounds;

swelling or rapid weight gain;

urinating less than usual or not at all;

dark urine, nausea, low fever, loss of appetite, clay-colored stools, jaundice, stomach pain ;

fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;

bruising, severe tingling, numbness, pain, muscle weakness;

fever, headache, neck stiffness, chills, increased sensitivity to light, purple spots on the skin, and/or seizure.

Less serious include:

upset stomach, mild heartburn or stomach pain, diarrhea, constipation;

bloating, gas;

dizziness, headache, nervousness;

skin itching or rash;

blurred vision;

ringing in your ears.

If you experience one of them stop using Feldene and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.

Drug interaction

Feldene interact with following drugs: a blood thinner such as warfarin; lithium; methotrexate;

diuretics such as furosemide; steroids; aspirin or other NSAIDs such as etodolac, flurbiprofen, indomethacin, ketoprofen, ketorolac, mefenamic acid, meloxicam, nabumetone, naproxen, and others;

an ACE inhibitor such as benazepril, captopril, fosinopril, enalapril, lisinopril, ramipril, and others.

Also note that interaction between two medications does not always mean that you must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.


Symptoms of Feldene overdose may include: stomach pain, nausea, drowsiness, vomiting, black or bloody stools, shallow breathing, coughing up blood, fainting, or coma. If you experience one of them or any unusual symptoms call your doctor immediately.


Store at room temperature between 20-25 C (68-77 F).


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Lasix work and what pharmaceutical group does it belong to?

Lasix is a diuretic agent. Lasix causes a short term diuresis. Lasix action mechanism is associated with the reabsorbtion block of chloride and sodium ions in the Henle's loop.Lasix works by increasing excretion of K+, Ca2+, Mg2+ out of the organism. Hypotensive effect of the medication is associated with increased elimination of sodium and water.

Which conditions are treated with Lasix?

Lasix is used for the treatment of the following conditions:

  • Edema syndrome in chronic cardiac failure(II - III stage)
  • Cirrhosis
  • Kidney diseases
  • Cerebral edema
  • Hypertensive crisis
  • Hypertension
  • High calcium blood level

What should a patient know before using Lasix?

The Lasix should not be used in cases of:

  • Hypersensitivity
  • Severe renal failure
  • Acute liver failure
  • Ankylurethria
  • Acute glomerulonephritis
  • Hyperglycemic coma
  • Hyperuricemia
  • Arthragra
  • Decompensated mitral or aortal stenosis
  • Hypotension
  • Acute myocardial infarction
  • Pancreatitis
  • Digitalis intoxication

The drug should be used with caution in the following conditions:

  • Prostatic Hyperplasia
  • Systemic lupus erythematosus
  • Diabetes
  • Pregnancy
  • Breastfeeding

Which adverse effects may manifest when using the medication?

The side effects of Lasix include:

  • Cardiovascular system: hypotension, postural hypotension, collapse, tachycardia, arrhythmia, volume of blood circulation decrease.
  • Central nervous system: dizziness, headache, myasthenia, cramp in leg, paresthesia, apathy, adynamia, weakness, drowsiness,
  • Sense organs: vision and hearing disorders.
  • Gastrointestinal tract: appetite reduce, xerostomia, nausea, vomiting, constipations and diarrhea, pancreatitis.
  • Urinary system: oliguria, acute retention of urine, interstitial nephritis, erythrocyturia, decrease of sexual potency.
  • Allergic reactions: purpura, urticaria fever, exfoliative dermatitis, vasculitis, skin rash, shakes, fever.
  • Hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis, anemotrophy.
  • Water-electrolyte balance: hypovolemia, anhydration, hypokalemia, hyponatremia, hypomagnesemia, metabolic alkalosis.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Lasix?

The drug is affected by the following:

  • Immunodepresants
  • Aminoglycosides
  • Antimicrobial agents
  • Diuretics
  • Antineoplastics
  • Antimycotics
  • Antiulcer agents
  • Bronchodilating agents
  • Hypotensive preparations
  • Glucocorticosteroids
  • Cardiac glycosides

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Lasix is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.