Generic Duricef (Cefadroxil)
Duricef is a cephalosporin antibiotic to treat infections of respiratory system, urinary tract, pelvic organs, skin and soft tissues, eye infections.
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Product Description

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Common use

Duricef belongs to the cephalosporin family of drugs, it causes bactericidal effect violating cell wall formation. It acts against a broad spectrum of gram positive bacteria like Staphylococcus. (both producing and non-producing penicillase) Streptococcus and gram negative microorganisms (Shigella, Salmonella, Escherichia coli, Haemophilus influenzae, Klebsiella, some strains of Proteus). This medication is used to treat infections of respiratory system, urinary tract, pelvic organs, skin and soft tissues, osteomyelitis, eye infections, etc. which are caused by susceptible microorganisms as well as for prevention of endocarditis, infectious complications after surgery.

Dosage and directions

This medication is recommended to take once or twice daily. A daily dose is 1-2 mg. Dosage is administered individually and should be corrected for children.


Avoid drinking alcohol during your course of treatment. Special attention should be paid to possibility of pseudomembranous colitis development and toxicity caused by Clostridium difficile. If symptoms of diarrhea are not serious they disappear after the medication intake was discontinued. Inform your doctor if you are pregnant or going to become pregnant before to take this drug.


Hypersensitivity to Durisef or penicillins and penicillamine, pregnancy, breastfeeding. Cautiousness should be exercised in patients with chronic kidney failure, colitis in history.

Possible side effect

You may experience diarrhea, inflammation of the bowel (colitis), nausea, redness and swelling of skin, skin rash and itching, vaginal inflammation, vomiting, seizures in rare cases and only your doctor make decide correctly if there is need for you to continue to take this drug.

Drug interaction

Durisef increases toxicity of polymixines and aminoglycosides, diuretics affecting loop of Henle in kidneys. Risk of bleeding increases in combination with inhibitors of platelets aggregation and non-steroid anti-inflammatory medications.

Missed dose

Never take a double dose of this medication. If you take Durisef once daily skip your missed dose and take the medication as soon as you remember, next dose should be taken in 10-12 hours. If you take Durisef twice daily the period between doses should be 5-6 hours.


In case of serious and persistent seizures, allergic reaction (hives, rash, swelling of face and tongue, vaginal itching), diarrhea or kidney failure consult your doctor.


Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term. Suspension can be used during 14 days after its preparation and should be kept in a refrigerator.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Lasix work and what pharmaceutical group does it belong to?

Lasix is a diuretic agent. Lasix causes a short term diuresis. Lasix action mechanism is associated with the reabsorbtion block of chloride and sodium ions in the Henle's loop.Lasix works by increasing excretion of K+, Ca2+, Mg2+ out of the organism. Hypotensive effect of the medication is associated with increased elimination of sodium and water.

Which conditions are treated with Lasix?

Lasix is used for the treatment of the following conditions:

  • Edema syndrome in chronic cardiac failure(II - III stage)
  • Cirrhosis
  • Kidney diseases
  • Cerebral edema
  • Hypertensive crisis
  • Hypertension
  • High calcium blood level

What should a patient know before using Lasix?

The Lasix should not be used in cases of:

  • Hypersensitivity
  • Severe renal failure
  • Acute liver failure
  • Ankylurethria
  • Acute glomerulonephritis
  • Hyperglycemic coma
  • Hyperuricemia
  • Arthragra
  • Decompensated mitral or aortal stenosis
  • Hypotension
  • Acute myocardial infarction
  • Pancreatitis
  • Digitalis intoxication

The drug should be used with caution in the following conditions:

  • Prostatic Hyperplasia
  • Systemic lupus erythematosus
  • Diabetes
  • Pregnancy
  • Breastfeeding

Which adverse effects may manifest when using the medication?

The side effects of Lasix include:

  • Cardiovascular system: hypotension, postural hypotension, collapse, tachycardia, arrhythmia, volume of blood circulation decrease.
  • Central nervous system: dizziness, headache, myasthenia, cramp in leg, paresthesia, apathy, adynamia, weakness, drowsiness,
  • Sense organs: vision and hearing disorders.
  • Gastrointestinal tract: appetite reduce, xerostomia, nausea, vomiting, constipations and diarrhea, pancreatitis.
  • Urinary system: oliguria, acute retention of urine, interstitial nephritis, erythrocyturia, decrease of sexual potency.
  • Allergic reactions: purpura, urticaria fever, exfoliative dermatitis, vasculitis, skin rash, shakes, fever.
  • Hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis, anemotrophy.
  • Water-electrolyte balance: hypovolemia, anhydration, hypokalemia, hyponatremia, hypomagnesemia, metabolic alkalosis.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Lasix?

The drug is affected by the following:

  • Immunodepresants
  • Aminoglycosides
  • Antimicrobial agents
  • Diuretics
  • Antineoplastics
  • Antimycotics
  • Antiulcer agents
  • Bronchodilating agents
  • Hypotensive preparations
  • Glucocorticosteroids
  • Cardiac glycosides

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Lasix is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.