Generic Diflucan (Fluconazole)
Diflucan
Diflucan is anti-fungal antibiotic used against candidiasis of different organs including genital area.
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Product Description

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Common use

Diflucan is an anti-fungal antibiotic which used to treat fungal infections called candidiasis. This medication is prescribed for treatment such type of infections as vaginal, throat and fungal infections, infections of the urinary tract, peritonitis, and pneumonia. Diflucan works by killing sensitive fungi by interfering with the formation of the fungal cell membrane.



Dosage and direction

Take it orally once a day, with or without food using the measuring spoon. Take it at the same time each day if you want to get best result with a full glass of water. Diflucan make you feel better after 24 hours. However, your symptoms go away completely just after few days. If there is no change in your health after a few days consult with your doctor immediately.

Dosage for adults various from type of infection and consist:

1) Genital thrush - 150mg as a single dose

2) Mucosal thrush - dose depends on where the infection is located 50mg once daily during month.

3)Fungal skin infections - 50mg once daily for 2-4 weeks ;

4) Internal fungal infections 400mg on the first day then 200-400mg once daily for 6-8 weeks or longer if needed.

5) To stop you from getting fungal infections - 50-400mg once daily while you have risk to get an infection;

6) To stop infection caused by Cryptococcus from coming back - 100-200mg once daily indefinitely

Dosage for children 4 weeks to 15 years old also various from type of infection and consist:

1) mucosal infections - 3mg/kg once daily;

2)internal fungal infections - 6-12mg/kg once daily;

3)prevention of fungal infections - 3-12mg/kg once daily while at risk of getting an infection.

For children 2-4 weeks old it is same dose as above but given once every 2 days. A maximum dose of 12mg/kg every 2 days.

For children less than 2 weeks old it is same dose as above but given once every 3 days. Do not give more then 12mg/kg every 3 days.

Note: this instruction presented here just for review. It's very necessary to consult with your doctor before using. It help you to get best results.



Precautions

For vaginal yeast infections, doctors usually prescribe a single dose of Diflucan. If the yeast infection does not improve after 5 days, contact your doctor as soon as possible. Be careful with this medication if your medical history include liver disease or kidney disease. Although uncommon, this drug may make you dizzy, so be more attentive while you are driving or using machinery. Limit alcohol intake. Diflucan should not be used during pregnancy, becoming pregnant or lactating without doctor's advice. Do not use before breast-feeding without doctor's advice.



Contraindications

Diflucan is not allowed to people which are hypersensitivity to Fluconazole or other anti fungal azole preparations, eg clotrimazole, ketoconazole, itraconazole and other. Also Diflucan contraindicated in:

Kidney and liver disorders;

Cardiovascular diseases including heart diseases(heart rate or rhythm disturbances);

Low blood levels of calcium, magnesium or potassium.



Possible side effect

They may include an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Also the most possible side effects include:

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

fever, chills, body aches, flu symptoms;

severe blistering, peeling, and red skin rash;

easy bruising or bleeding, unusual weakness; or

seizure (convulsions).

Less serious include:

mild nausea, vomiting, diarrhea, or upset stomach;

headache;

dizziness;

unusual or unpleasant taste in your mouth; or

skin rash or itching.

If you experience one of them stop using Diflucan and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.



Drug interaction

Diflucan interact with such medication as:

a blood thinner such as warfarin (Coumadin)

cyclosporine (Gengraf, Sandimmune, Neoral);

an oral diabetes medicine such as glipizide (Glucotrol), glyburide (Diabeta, Micronase, Glynase), tolbutamide (Orinase), tolazamide (Tolinase), chlorpropamide (Diabinese), and others;

rifabutin (Mycobutin) or rifampin (Rifadin, Rifater, Rifamate, Rimactane);

a sedative such as diazepam (Valium), lorazepam (Ativan), alprazolam (Xanax), or midazolam (Versed);

seizure medication such as phenytoin (Dilantin) or valproic acid (Depakene);

tacrolimus ((Prograf);

theophylline (Theo-Dur, Theolair, Theochron, Elixophyllin, Slo-Phyllin, others).

Also note that interaction between two medications does not always mean that you

must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.



Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not take double or extra doses. Take your usually dose next day in the same regularly time.



Overdose

Symptoms of Diflucan overdose may include: confusion or unusual thoughts or behavior. If you experience one of them call your doctor immediately.



Storage

Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Lasix work and what pharmaceutical group does it belong to?

Lasix is a diuretic agent. Lasix causes a short term diuresis. Lasix action mechanism is associated with the reabsorbtion block of chloride and sodium ions in the Henle's loop.Lasix works by increasing excretion of K+, Ca2+, Mg2+ out of the organism. Hypotensive effect of the medication is associated with increased elimination of sodium and water.

Which conditions are treated with Lasix?

Lasix is used for the treatment of the following conditions:

  • Edema syndrome in chronic cardiac failure(II - III stage)
  • Cirrhosis
  • Kidney diseases
  • Cerebral edema
  • Hypertensive crisis
  • Hypertension
  • High calcium blood level

What should a patient know before using Lasix?

The Lasix should not be used in cases of:

  • Hypersensitivity
  • Severe renal failure
  • Acute liver failure
  • Ankylurethria
  • Acute glomerulonephritis
  • Hyperglycemic coma
  • Hyperuricemia
  • Arthragra
  • Decompensated mitral or aortal stenosis
  • Hypotension
  • Acute myocardial infarction
  • Pancreatitis
  • Digitalis intoxication

The drug should be used with caution in the following conditions:

  • Prostatic Hyperplasia
  • Systemic lupus erythematosus
  • Diabetes
  • Pregnancy
  • Breastfeeding

Which adverse effects may manifest when using the medication?

The side effects of Lasix include:

  • Cardiovascular system: hypotension, postural hypotension, collapse, tachycardia, arrhythmia, volume of blood circulation decrease.
  • Central nervous system: dizziness, headache, myasthenia, cramp in leg, paresthesia, apathy, adynamia, weakness, drowsiness,
  • Sense organs: vision and hearing disorders.
  • Gastrointestinal tract: appetite reduce, xerostomia, nausea, vomiting, constipations and diarrhea, pancreatitis.
  • Urinary system: oliguria, acute retention of urine, interstitial nephritis, erythrocyturia, decrease of sexual potency.
  • Allergic reactions: purpura, urticaria fever, exfoliative dermatitis, vasculitis, skin rash, shakes, fever.
  • Hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis, anemotrophy.
  • Water-electrolyte balance: hypovolemia, anhydration, hypokalemia, hyponatremia, hypomagnesemia, metabolic alkalosis.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Lasix?

The drug is affected by the following:

  • Immunodepresants
  • Aminoglycosides
  • Antimicrobial agents
  • Diuretics
  • Antineoplastics
  • Antimycotics
  • Antiulcer agents
  • Bronchodilating agents
  • Hypotensive preparations
  • Glucocorticosteroids
  • Cardiac glycosides
  • NSAID

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Lasix is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.