Generic Crestor (Rosuvastatin)
Crestor treats high cholesterol and atherosclerosis, it is a drug from class of statins.
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Common use

Crestor is a cholesterol-lowering medication which used to lower cholesterol levels when diet and exercise alone have failed to work.

Dosage and direction

Take this medication with or without food, at any time once a day. Swallow each tablet whole with a drink of water/milk.

Commonly dose of Crestor is 5 to 40 mg. Dosage of 40 mg is using for patients not reaching LDL-C goal with 20 mg.

Hyperlipidemia, mixed dyslipidemia, hypertriglyceridemia, and atherosclerosis: Starting dose 10 mg. Cresor 20 mg is a starting dose for patients with LDL-C >190 mg/dL and aggressive lipid targets.

HoFH: Starting dose is 20 mg.

This drug is only a small part of a whole program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very carefully.

Note: this instruction presented here just for review. It's very necessary to consult with your doctor before using. It help you to get best results.


Do not take if you have any liver problems or have ever had a disease which affected your liver; if you have any kidney problems; if you have been told that you have a condition affecting your muscles called myopathy; if you are taking the immunosuppressive drug, cyclosporin; if you are pregnant or if there is a possibility that you may become pregnant; if you are breast-feeding. Consult with your doctor if you are taking any other medicines, including those which you may have bought over the counter. In particular tell your doctor if you are taking any of the following: gemfibrozil, cyclosporin, warfarin, antacids, erythromycin or an oral contraceptive.


Crestor is contraindicated in patients:

- with hypersensitivity to rosuvastatin or to any of the excipients;

- with active liver disease;

- with severe renal impairment;

- with myopathy;

- receiving concomitant ciclosporin;

- during pregnancy and lactation and in women of childbearing potential not using appropriate contraceptive measures;

The 40 mg dose is contraindicated in patients with pre-disposing factors for myopathy/rhabdomyolysis. Such factors include:

в€’ moderate renal impairment;

в€’ hypothyroidism;

в€’ personal or family history of hereditary muscular disorders;

в€’ previous history of muscular toxicity with another HMG-CoA reductase inhibitor or fibrate;

в€’ alcohol abuse;

в€’ situations where an increase in plasma levels may occur ;

в€’ Asian patients;

в€’ concomitant use of fibrates.

Possible side effect

They may include all types of an allergic reaction. Also the most possible side effects include:

muscle pain, tenderness, or weakness with fever or flu symptoms and dark colored urine;

urinating more or less than usual, or not at all;

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

chest pain; or

swelling in your hands or feet.

Less serious include:

weakness, dizziness;

mild nausea, constipation, diarrhea;

sore throat, runny or stuffy nose;

memory loss;

headache; or

pain or burning when you urinate.

If you experience one of them stop using Crestor and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.

Drug interaction

Do not take this medicine with any of the following medications: herbal medicines like red yeast rice or other medicines for high cholesterol

This medicine may also interact with the following medications: alcohol, antacids containing aluminum hydroxide or magnesium hydroxide, cyclosporine, niacin, warfarin.

Also note that interaction between two medications does not always mean that you

must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.


The symptoms of a Crestor overdose are not known well. Most possible of them include: liver damage, kidney failure, pancreatitis, yellow skin (jaundice), serious breakdown of muscle (known as rhabdomyolysis). If you experience one of them call your doctor immediately.


Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Lasix work and what pharmaceutical group does it belong to?

Lasix is a diuretic agent. Lasix causes a short term diuresis. Lasix action mechanism is associated with the reabsorbtion block of chloride and sodium ions in the Henle's loop.Lasix works by increasing excretion of K+, Ca2+, Mg2+ out of the organism. Hypotensive effect of the medication is associated with increased elimination of sodium and water.

Which conditions are treated with Lasix?

Lasix is used for the treatment of the following conditions:

  • Edema syndrome in chronic cardiac failure(II - III stage)
  • Cirrhosis
  • Kidney diseases
  • Cerebral edema
  • Hypertensive crisis
  • Hypertension
  • High calcium blood level

What should a patient know before using Lasix?

The Lasix should not be used in cases of:

  • Hypersensitivity
  • Severe renal failure
  • Acute liver failure
  • Ankylurethria
  • Acute glomerulonephritis
  • Hyperglycemic coma
  • Hyperuricemia
  • Arthragra
  • Decompensated mitral or aortal stenosis
  • Hypotension
  • Acute myocardial infarction
  • Pancreatitis
  • Digitalis intoxication

The drug should be used with caution in the following conditions:

  • Prostatic Hyperplasia
  • Systemic lupus erythematosus
  • Diabetes
  • Pregnancy
  • Breastfeeding

Which adverse effects may manifest when using the medication?

The side effects of Lasix include:

  • Cardiovascular system: hypotension, postural hypotension, collapse, tachycardia, arrhythmia, volume of blood circulation decrease.
  • Central nervous system: dizziness, headache, myasthenia, cramp in leg, paresthesia, apathy, adynamia, weakness, drowsiness,
  • Sense organs: vision and hearing disorders.
  • Gastrointestinal tract: appetite reduce, xerostomia, nausea, vomiting, constipations and diarrhea, pancreatitis.
  • Urinary system: oliguria, acute retention of urine, interstitial nephritis, erythrocyturia, decrease of sexual potency.
  • Allergic reactions: purpura, urticaria fever, exfoliative dermatitis, vasculitis, skin rash, shakes, fever.
  • Hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis, anemotrophy.
  • Water-electrolyte balance: hypovolemia, anhydration, hypokalemia, hyponatremia, hypomagnesemia, metabolic alkalosis.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Lasix?

The drug is affected by the following:

  • Immunodepresants
  • Aminoglycosides
  • Antimicrobial agents
  • Diuretics
  • Antineoplastics
  • Antimycotics
  • Antiulcer agents
  • Bronchodilating agents
  • Hypotensive preparations
  • Glucocorticosteroids
  • Cardiac glycosides

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Lasix is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.