Generic Colospa (Mebeverine)
Colospa causes relaxation of the muscles, preventing painful muscle spasms. The drug is used in the treatment of irritable bowel syndrome.
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135 mg x 30 pills
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135 mg x 60 pills
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135 mg x 240 pills
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Product Description

Colospa - are

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Common use

Colospa is a musculotropic antispasmodic medication used in the treatment of irritable bowel syndrome. It is also indicated for treatment of gastrointestinal spasm caused by a primal organic disorder. Mechanism of its action consists in relaxing of gut muscles at the cellular level. Colospa blocks transfer of Na+ through fast channels of myocyte into th cell and also inhibits calcium-depot replenishment, thus it performs a dual effect on bowels causing them to relax. It does not affect muscles of bronchi or uterus. No significant inhibition of normal peristalsis has been observed. This drug is used to treat a spasm of gastrointestinal organs (including due to organic disease), intestinal colic, biliary colic, irritable bowel syndrome (symptomatic treatment of pain and cramps, and intestinal disorders and discomfort) in adults.

Dosage and directions

Recommended daily dose of Colospa is 135 mg (1 tablet) 3 times daily, preferably before meals. Gradually the dosage may be reduced when the desired effect has been obtained.


In pregnant patients Colospa is possible to use when expected benefit of treatment exceeds potential risk for the unborn baby. Avoid driving or be specially cautious when you need to drive or operate any machinery and mechanisms due to the possible dizziness caused by Colospa. Carefulness should be exercised in patients with paralytic ileus which is obstruction caused by failure of function of the intestine. This medicine is not recommended to treat children under 10 years of age. Discuss with your doctor if you suffer from inactivity of the bowel or allergic to any sugars before to take Colospa.


Hypersensitivity, porphyria.

Possible side effect

Any medication may affect different people individually, symptoms of allergy (hives, rash, swelling of face) may appear. If you need more information about any other possible risks associated with Colospa, you should consult your doctor or pharmacist.

Drug interaction

This medicine is not known to interact with other medication.

Missed dose

If you missed a dose take the medication as soon as you remember. If it is almost time of your next dose just skip its intake and return to your regular schedule.


Overdose symptoms are unknown or may appear as over excitation of the central nervous system. Anyway if consider that you took too much of this medication consult your doctor, as you may need medical help.


Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Lasix work and what pharmaceutical group does it belong to?

Lasix is a diuretic agent. Lasix causes a short term diuresis. Lasix action mechanism is associated with the reabsorbtion block of chloride and sodium ions in the Henle's loop.Lasix works by increasing excretion of K+, Ca2+, Mg2+ out of the organism. Hypotensive effect of the medication is associated with increased elimination of sodium and water.

Which conditions are treated with Lasix?

Lasix is used for the treatment of the following conditions:

  • Edema syndrome in chronic cardiac failure(II - III stage)
  • Cirrhosis
  • Kidney diseases
  • Cerebral edema
  • Hypertensive crisis
  • Hypertension
  • High calcium blood level

What should a patient know before using Lasix?

The Lasix should not be used in cases of:

  • Hypersensitivity
  • Severe renal failure
  • Acute liver failure
  • Ankylurethria
  • Acute glomerulonephritis
  • Hyperglycemic coma
  • Hyperuricemia
  • Arthragra
  • Decompensated mitral or aortal stenosis
  • Hypotension
  • Acute myocardial infarction
  • Pancreatitis
  • Digitalis intoxication

The drug should be used with caution in the following conditions:

  • Prostatic Hyperplasia
  • Systemic lupus erythematosus
  • Diabetes
  • Pregnancy
  • Breastfeeding

Which adverse effects may manifest when using the medication?

The side effects of Lasix include:

  • Cardiovascular system: hypotension, postural hypotension, collapse, tachycardia, arrhythmia, volume of blood circulation decrease.
  • Central nervous system: dizziness, headache, myasthenia, cramp in leg, paresthesia, apathy, adynamia, weakness, drowsiness,
  • Sense organs: vision and hearing disorders.
  • Gastrointestinal tract: appetite reduce, xerostomia, nausea, vomiting, constipations and diarrhea, pancreatitis.
  • Urinary system: oliguria, acute retention of urine, interstitial nephritis, erythrocyturia, decrease of sexual potency.
  • Allergic reactions: purpura, urticaria fever, exfoliative dermatitis, vasculitis, skin rash, shakes, fever.
  • Hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis, anemotrophy.
  • Water-electrolyte balance: hypovolemia, anhydration, hypokalemia, hyponatremia, hypomagnesemia, metabolic alkalosis.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Lasix?

The drug is affected by the following:

  • Immunodepresants
  • Aminoglycosides
  • Antimicrobial agents
  • Diuretics
  • Antineoplastics
  • Antimycotics
  • Antiulcer agents
  • Bronchodilating agents
  • Hypotensive preparations
  • Glucocorticosteroids
  • Cardiac glycosides

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Lasix is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.