Generic Cardarone (Amiodarone)
Cardarone is used in treatment of irregular heartbeat and to maintain a normal heart rate (ventricular fibrillation and ventricular tachycardia).
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Common use

The medication causes antiarrhythmic and antianginal effects. Antiarrhythmic effect is stipulated by diminishing of K+ ions transportation though cell membranes of myocites and diminishing of sinus node automaticity. Cardarone automatically blocks a- and b-adrenoreceptors. Relief of paroxysmal tachycardia attacks, relief of other heart attacks and treatment of ventricular fibrillation. Cardarone is for use only in life-threatening situations and should be used strictly according to recommendations of your doctor.

Dosage and direction

Cardarone may hurt stomach so it is recommended to take it with meals and in several daily doses to minimize damage.


Avoid drinking grapefruit juice, tanning and excessive UV irradiation, be careful doing work which requires high concentration of attention (driving and others).


Hypersensitivity to iodium or Cardarone. Sick sinus syndrome (sinus bradycardia, sinoatrial block) excluding cases of rythm correction with artificial pacemake. Disorders of atrioventricular or intra ventricular conduction (atrioventricular blocade of I-III degree), blocade of bundle Branch Block, disorders of thyroid gland, hypopotassiemia, pregnancy, breast-feeding, age below 18 years old, simultaneous treatment with MAO inhibitors.

Possible side effect

Lipofuscin deposit in cornea may cause appearance of shining spots or a 'fog' in front of eyes at bright light. Light pygmentation on open areas of skin, hypothyreosis, wheezing, cough, chest pain, trouble breathing, weight loss, thinning hair, feeling too hot or too cold, numbness, burning, pain, nausea, stomach pain. Call your doctor if you experience this or symptoms of allergy.

Drug interaction

Cardarone may interact with beta-blockers or certain calcium channel blockers leading to excessively slow heart rate or electrical impulse blockage in the heart. Blood levels of digoxin are increased at concurrent treatment with digoxin and Amiodarone. In case of treatment with digoxin its dose should be decreased by 50% when amiodarone is taken. Cardarone also increases levels of flecainide, procainamide and quinidine.

Missed dose

If you missed a dose take it as soon as you remember, but not if it is almost time of the next intake by your schedule. If it occurred skip the missed dose. Do not try to compensate a missed dose by taking an extra one.


If you suspect that you took too much of the medication and experience extremely dizzy or light-headed, or fainting seek for immediate medical attention.


Keep Cordarone at room temperature, lower than 30 C (86 F).


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. РђРїСѓ specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Lasix work and what pharmaceutical group does it belong to?

Lasix is a diuretic agent. Lasix causes a short term diuresis. Lasix action mechanism is associated with the reabsorbtion block of chloride and sodium ions in the Henle's loop.Lasix works by increasing excretion of K+, Ca2+, Mg2+ out of the organism. Hypotensive effect of the medication is associated with increased elimination of sodium and water.

Which conditions are treated with Lasix?

Lasix is used for the treatment of the following conditions:

  • Edema syndrome in chronic cardiac failure(II - III stage)
  • Cirrhosis
  • Kidney diseases
  • Cerebral edema
  • Hypertensive crisis
  • Hypertension
  • High calcium blood level

What should a patient know before using Lasix?

The Lasix should not be used in cases of:

  • Hypersensitivity
  • Severe renal failure
  • Acute liver failure
  • Ankylurethria
  • Acute glomerulonephritis
  • Hyperglycemic coma
  • Hyperuricemia
  • Arthragra
  • Decompensated mitral or aortal stenosis
  • Hypotension
  • Acute myocardial infarction
  • Pancreatitis
  • Digitalis intoxication

The drug should be used with caution in the following conditions:

  • Prostatic Hyperplasia
  • Systemic lupus erythematosus
  • Diabetes
  • Pregnancy
  • Breastfeeding

Which adverse effects may manifest when using the medication?

The side effects of Lasix include:

  • Cardiovascular system: hypotension, postural hypotension, collapse, tachycardia, arrhythmia, volume of blood circulation decrease.
  • Central nervous system: dizziness, headache, myasthenia, cramp in leg, paresthesia, apathy, adynamia, weakness, drowsiness,
  • Sense organs: vision and hearing disorders.
  • Gastrointestinal tract: appetite reduce, xerostomia, nausea, vomiting, constipations and diarrhea, pancreatitis.
  • Urinary system: oliguria, acute retention of urine, interstitial nephritis, erythrocyturia, decrease of sexual potency.
  • Allergic reactions: purpura, urticaria fever, exfoliative dermatitis, vasculitis, skin rash, shakes, fever.
  • Hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis, anemotrophy.
  • Water-electrolyte balance: hypovolemia, anhydration, hypokalemia, hyponatremia, hypomagnesemia, metabolic alkalosis.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Lasix?

The drug is affected by the following:

  • Immunodepresants
  • Aminoglycosides
  • Antimicrobial agents
  • Diuretics
  • Antineoplastics
  • Antimycotics
  • Antiulcer agents
  • Bronchodilating agents
  • Hypotensive preparations
  • Glucocorticosteroids
  • Cardiac glycosides

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Lasix is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.