Generic Calan Sr (Verapamil)
Calan Sr
Calan Sr is a calcium channel blocker, it is effective in treatment of hypertension, stenocardia, etc.
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Common use

Calan is used to treat hypertension, hypertensive crisis, primary pulmonary hypertension, stenocardia, supraventricular tachicardia, sinus tachycardia, atrial tachyarrhythmia, atrial flutter, atrial arrhythmia.

Dosage and direction

Patients with stenocardia or supraventricular tachicardia should take Calan three times a day, those with arterial hypertension taken it twice a day. Dosage depends on the disease, age and should be individually administered depending on severeness of the condition. Consult your doctor before to take the medication.


Calan can influence thinking or reactions, thus special carefulness is necessary during driving or actions requiring concentration of attention and fast reaction. Do not get up too fast if you sit or lie as it may cause dizziness. Avoid drinking alcohol and consult your doctor if you drink grapefruit juice as its interaction with Calan may lead to potentially dangerous effects.


Hypersensitivity, severe arterial hypotension pregnancy, breast-feeding, atrioventricular block (first and second degree), sinoatrial blockade, sick sinus syndrome (except of the patients with a cardiostimulator), Wolff-Parkinson-White syndrome (WPW), Lown-Ganong-Levine syndrome in combination with atrial fibrillation/flutter. Some other conditions require careful use of Calan. Do not take the medication unless it is prescribed to you and take it only as it is administered by your physician.

Possible side effect

Usual side effects of Calan are constipation, dizziness, nausea, low blood pressure, headaches. If more serious symptoms as chest pain, an irregular heart rhythm (arrhythmia) or a slow heart rate (bradycardia), heart attacks or strokes, significant water retention, especially accompanied by difficulty breathing, signs of very low blood pressure, such as dizziness, lightheadedness, or fainting, hallucinations or other psychotic problems, any signs of an allergic reaction, including an unexplained rash, hives, itching, unexplained swelling, wheezing, or difficulty breathing or swallowing are observed, seek for immediate medical attention.

Drug interaction

Dangerous heart slowing may appear if Calan is taken concurrently with a beta blocker. This medication increases concentration of digoxin, theophylline, carbamazepine, myorelaxants in blood so levels of these drugs should be monitored to avoid toxicity. In some patients blood levels of lithium maybe reduced.

Missed dose

If you missed a dose take it as soon as you remember, but not if it is almost time of the next intake by your schedule. If so skip the missed dose. Do not try to compensate a missed dose by taking an extra one.


If you suspect that you took too much of Calan and feel slow heartbeat and fainting seek for immediate medical attention.


The medication should be stored at room temperature 15-30 C (59-86 F) in a light- resistant box.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Lasix work and what pharmaceutical group does it belong to?

Lasix is a diuretic agent. Lasix causes a short term diuresis. Lasix action mechanism is associated with the reabsorbtion block of chloride and sodium ions in the Henle's loop.Lasix works by increasing excretion of K+, Ca2+, Mg2+ out of the organism. Hypotensive effect of the medication is associated with increased elimination of sodium and water.

Which conditions are treated with Lasix?

Lasix is used for the treatment of the following conditions:

  • Edema syndrome in chronic cardiac failure(II - III stage)
  • Cirrhosis
  • Kidney diseases
  • Cerebral edema
  • Hypertensive crisis
  • Hypertension
  • High calcium blood level

What should a patient know before using Lasix?

The Lasix should not be used in cases of:

  • Hypersensitivity
  • Severe renal failure
  • Acute liver failure
  • Ankylurethria
  • Acute glomerulonephritis
  • Hyperglycemic coma
  • Hyperuricemia
  • Arthragra
  • Decompensated mitral or aortal stenosis
  • Hypotension
  • Acute myocardial infarction
  • Pancreatitis
  • Digitalis intoxication

The drug should be used with caution in the following conditions:

  • Prostatic Hyperplasia
  • Systemic lupus erythematosus
  • Diabetes
  • Pregnancy
  • Breastfeeding

Which adverse effects may manifest when using the medication?

The side effects of Lasix include:

  • Cardiovascular system: hypotension, postural hypotension, collapse, tachycardia, arrhythmia, volume of blood circulation decrease.
  • Central nervous system: dizziness, headache, myasthenia, cramp in leg, paresthesia, apathy, adynamia, weakness, drowsiness,
  • Sense organs: vision and hearing disorders.
  • Gastrointestinal tract: appetite reduce, xerostomia, nausea, vomiting, constipations and diarrhea, pancreatitis.
  • Urinary system: oliguria, acute retention of urine, interstitial nephritis, erythrocyturia, decrease of sexual potency.
  • Allergic reactions: purpura, urticaria fever, exfoliative dermatitis, vasculitis, skin rash, shakes, fever.
  • Hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis, anemotrophy.
  • Water-electrolyte balance: hypovolemia, anhydration, hypokalemia, hyponatremia, hypomagnesemia, metabolic alkalosis.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Lasix?

The drug is affected by the following:

  • Immunodepresants
  • Aminoglycosides
  • Antimicrobial agents
  • Diuretics
  • Antineoplastics
  • Antimycotics
  • Antiulcer agents
  • Bronchodilating agents
  • Hypotensive preparations
  • Glucocorticosteroids
  • Cardiac glycosides

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Lasix is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.