Brand Levitra (Vardenafil)
Brand Levitra
Brand Levitra causes widening and relaxation of the blood vessels carrying blood to the penis.
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Common use

Brand Levitra was developed by the pharmaceutical company Bayer/GlaxoSmithKline and uses Vardenafil HCl as main component of the medication. Levitra is an oral drug used to treat erectile dysfunction. Sexual stimulation causes the production and release of nitric oxide from the nerves endings of the cavernous bodies of the penis hereby activating enzyme guanylate cyclase. Guanylate cyclase in its turn is responsible for production of cyclic guanosine monophosphate (cGMP). The cGMP causes widening and relaxation of the blood vessels carrying blood to the penis. Levitra prevents phosphodiesterase-5 enzyme from destroying cGMP and thus helps to support blood flow to the penis.



Dosage and direction

The recommended dose of Levitra is 10 mg per day taken an hour before intercourse. If no side effects are experienced the dosage can be increased up to 20 mg. In case of adverse effects the dose is reduced to 5 mg daily. Do not take more than one tab of Levitra a day.



Precautions

Levitra has not been studied in people with cardiovascular disease, so it is preferable to avoid Levitra if in patients who have a stroke or heart failure, or a heart attack in history and especially within last six month. Before to take Levitra inform your doctor if you have kidney or liver problems, a bleeding disorder, stomach ulcer, or an inherited retinal disorder such as retinitis pigmentosa, allergic reaction to this medicine or any other medicines, deformation of the penis such as angulation, cavernous fibrosis (Peyronie's disease), as well as in diseases that contribute to the development of priapism (sickle-cell anemia, multiple myeloma, leukemia, or leukemia).



Contraindications

Levitra is contraindicated in patients with hypersensitivity to its ingredients, ones treated with organic nitrates, in patients under 16 y.o., or those who take HIV protease inhibitors such as indinavir and ritonavir.



Possible side effect

Levitra is usually well tolerated and side effects if occur are transient. The most frequent side effects are: headache, flushing (hyperemia of the person); frequent; dizziness, diarrhea phenomenon, nausea, nasal congestion. More rare and uncommon adverse effects are photosensitivity of skin, hypertension, back pain, watery eyes, hypotension, myalgia, priapism.



Drug interaction

Levitra's metabolism is inhibited by erythromycin, ketoconazole (Nizoral), itraconazole (Sporanox), indinavir (Crixivan) and ritonavir (Norvir). Levitra reduces the concentration of ritonavir and indinavir. In patients treated with nitrates Levitra may aggravate chest pain by increasing heart rate and lowering blood pressure. Levitra is able to exaggerate the blood pressure lowering effects of alpha-blocking drugs (terazosin or Hytrin). Levitra never should be administered in patients who are treated with organic nitrates.



Missed dose

Levitra is taken when needed but not more often than once daily so missed dose is not supposed.



Overdose

Symptoms of overdose include pain in the back, jaw, arm, blindness, blurred vision, chest pain or discomfort, decreased vision, blurred vision.



Storage

Store at room temperature between 15-30 C (59-86 F) away from children, pets, moisture and sunlight.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Lasix work and what pharmaceutical group does it belong to?

Lasix is a diuretic agent. Lasix causes a short term diuresis. Lasix action mechanism is associated with the reabsorbtion block of chloride and sodium ions in the Henle's loop.Lasix works by increasing excretion of K+, Ca2+, Mg2+ out of the organism. Hypotensive effect of the medication is associated with increased elimination of sodium and water.

Which conditions are treated with Lasix?

Lasix is used for the treatment of the following conditions:

  • Edema syndrome in chronic cardiac failure(II - III stage)
  • Cirrhosis
  • Kidney diseases
  • Cerebral edema
  • Hypertensive crisis
  • Hypertension
  • High calcium blood level

What should a patient know before using Lasix?

The Lasix should not be used in cases of:

  • Hypersensitivity
  • Severe renal failure
  • Acute liver failure
  • Ankylurethria
  • Acute glomerulonephritis
  • Hyperglycemic coma
  • Hyperuricemia
  • Arthragra
  • Decompensated mitral or aortal stenosis
  • Hypotension
  • Acute myocardial infarction
  • Pancreatitis
  • Digitalis intoxication

The drug should be used with caution in the following conditions:

  • Prostatic Hyperplasia
  • Systemic lupus erythematosus
  • Diabetes
  • Pregnancy
  • Breastfeeding

Which adverse effects may manifest when using the medication?

The side effects of Lasix include:

  • Cardiovascular system: hypotension, postural hypotension, collapse, tachycardia, arrhythmia, volume of blood circulation decrease.
  • Central nervous system: dizziness, headache, myasthenia, cramp in leg, paresthesia, apathy, adynamia, weakness, drowsiness,
  • Sense organs: vision and hearing disorders.
  • Gastrointestinal tract: appetite reduce, xerostomia, nausea, vomiting, constipations and diarrhea, pancreatitis.
  • Urinary system: oliguria, acute retention of urine, interstitial nephritis, erythrocyturia, decrease of sexual potency.
  • Allergic reactions: purpura, urticaria fever, exfoliative dermatitis, vasculitis, skin rash, shakes, fever.
  • Hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis, anemotrophy.
  • Water-electrolyte balance: hypovolemia, anhydration, hypokalemia, hyponatremia, hypomagnesemia, metabolic alkalosis.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Lasix?

The drug is affected by the following:

  • Immunodepresants
  • Aminoglycosides
  • Antimicrobial agents
  • Diuretics
  • Antineoplastics
  • Antimycotics
  • Antiulcer agents
  • Bronchodilating agents
  • Hypotensive preparations
  • Glucocorticosteroids
  • Cardiac glycosides
  • NSAID

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Lasix is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.