Generic Actigall (Ursodeoxycholic acid)
Actigall is used to treat small gallstones, to prevent gallstones, to treat primary biliary cirrhosis.
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Product Description

Regret: Actigall

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Common use

Actigall is a bile acid that decreases the amount of cholesterol produced by the liver and absorbed by the intestines. It helps break down cholesterol formed into stones in the gallbladder. Actigall also increases bile flow in patients with primary biliary cirrhosis. Actigall is used to treat small gallstones in people who cannot have gallbladder surgery. It is also used to prevent gallstones in people on rapid-weight-loss diets, it may also be used for purposes other than those listed in this medication guide, to treat primary biliary cirrhosis. Actigall is not used for treating gallstones that are calcified.

Dosage and direction

Take this medication exactly as directed by your doctor. Dosage is based on your medical condition and response to therapy. Your condition will not improve any faster, and the risk of serious side effects may be increased.Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.


Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Actigall. Also talk to your doctor about your complete medical history. Do not take these medications if you are sensitive to or have ever had an allergic reaction to ursodiol or to other bile acids. If you have biliary tract (liver, gallbladder, bile duct) problems or certain liver and pancreas diseases, your doctor may not be able to prescribe Actigall for you. Before taking Actigall, tell your doctor or pharmacist if you are allergic to it; or to other bile acids; or if you have any other allergies. This medication should not be used if you have certain medical conditions. This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.


Actigall will not dissolve calcified cholesterol stones, radiopaque stones, or radiolucent bile pigment stones. Hence, patients with such stones are not candidates for Actigall therapy. Patients with compelling reasons for cholecystectomy including unremitting acute cholecystitis, cholangitis, biliary obstruction, gallstone pancreatitis, or biliary-gastrointestinal fistula are not candidates for Actigall therapy. Allergy to bile acids.

Possible side effects

Stomach upset, nausea, diarrhea, dizziness, back pain, hair loss, or cough may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor immediately if any of these unlikely but serious side effects occur: weakness, swelling of the ankles, feet, increased thirst/urination, signs of infection (fever, persistent sore throat). It is rare to have a very serious allergic reaction to this drug. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling (especially of the face, tongue, throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Drug interactions

If Actigall is taken with certain other drugs, the effects of either could be increased, decreased, or altered. You have to check especially important with your doctor using of Actigall with the next medicines: aluminum-based antacid medications, cholesterol-lowering medications, estrogens, and oral contraceptives. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. Before using this medication, tell your doctor or pharmacist about all prescription and nonprescription/herbal products you may use, especially: aluminum-containing antacids, birth control pills, cholesterol medications (cholestyramine, clofibrate, colestipol), estrogen.

Missed dose

Take it as soon as you remember, or at the same time as the next dose.


Do not increase your dose or take this medication more often without your doctor's approval. If overdose is suspected, contact your local poison control center or emergency room immediately.


Store at room temperature in a tightly closed container.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Lasix work and what pharmaceutical group does it belong to?

Lasix is a diuretic agent. Lasix causes a short term diuresis. Lasix action mechanism is associated with the reabsorbtion block of chloride and sodium ions in the Henle's loop.Lasix works by increasing excretion of K+, Ca2+, Mg2+ out of the organism. Hypotensive effect of the medication is associated with increased elimination of sodium and water.

Which conditions are treated with Lasix?

Lasix is used for the treatment of the following conditions:

  • Edema syndrome in chronic cardiac failure(II - III stage)
  • Cirrhosis
  • Kidney diseases
  • Cerebral edema
  • Hypertensive crisis
  • Hypertension
  • High calcium blood level

What should a patient know before using Lasix?

The Lasix should not be used in cases of:

  • Hypersensitivity
  • Severe renal failure
  • Acute liver failure
  • Ankylurethria
  • Acute glomerulonephritis
  • Hyperglycemic coma
  • Hyperuricemia
  • Arthragra
  • Decompensated mitral or aortal stenosis
  • Hypotension
  • Acute myocardial infarction
  • Pancreatitis
  • Digitalis intoxication

The drug should be used with caution in the following conditions:

  • Prostatic Hyperplasia
  • Systemic lupus erythematosus
  • Diabetes
  • Pregnancy
  • Breastfeeding

Which adverse effects may manifest when using the medication?

The side effects of Lasix include:

  • Cardiovascular system: hypotension, postural hypotension, collapse, tachycardia, arrhythmia, volume of blood circulation decrease.
  • Central nervous system: dizziness, headache, myasthenia, cramp in leg, paresthesia, apathy, adynamia, weakness, drowsiness,
  • Sense organs: vision and hearing disorders.
  • Gastrointestinal tract: appetite reduce, xerostomia, nausea, vomiting, constipations and diarrhea, pancreatitis.
  • Urinary system: oliguria, acute retention of urine, interstitial nephritis, erythrocyturia, decrease of sexual potency.
  • Allergic reactions: purpura, urticaria fever, exfoliative dermatitis, vasculitis, skin rash, shakes, fever.
  • Hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis, anemotrophy.
  • Water-electrolyte balance: hypovolemia, anhydration, hypokalemia, hyponatremia, hypomagnesemia, metabolic alkalosis.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Lasix?

The drug is affected by the following:

  • Immunodepresants
  • Aminoglycosides
  • Antimicrobial agents
  • Diuretics
  • Antineoplastics
  • Antimycotics
  • Antiulcer agents
  • Bronchodilating agents
  • Hypotensive preparations
  • Glucocorticosteroids
  • Cardiac glycosides

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Lasix is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.